• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

灵长类动物对煤油的吸收。

Kerosene absorption in primates.

作者信息

Mann M D, Pirie D J, Wolfsdorf J

出版信息

J Pediatr. 1977 Sep;91(3):495-8. doi: 10.1016/s0022-3476(77)81334-6.

DOI:10.1016/s0022-3476(77)81334-6
PMID:408472
Abstract

Kerosene, labeled with 3H-toluene or 14C-hexadecane, was given to baboons by nasogastric tube after a tracheostomy had been performed. Six hours later the animals were killed and samples of tissues taken for analysis. The radioactive label was recovered from all the tissues analyzed. 3H-toluene appeared to be absorbed and taken up by most tissues to a greater extent than was 14C-hexadecane. No abnormal neurologic signs or behavior was noted in the baboons which were conscious during the study period. It appears that primates absorb kerosene from the gastrointestinal tract, but the volumes are very small and do not cause gross neurologic signs.

摘要

在给狒狒实施气管切开术后,通过鼻胃管给它们喂食用³H - 甲苯或¹⁴C - 十六烷标记的煤油。6小时后处死动物,采集组织样本进行分析。在所有分析的组织中都检测到了放射性标记物。³H - 甲苯似乎比¹⁴C - 十六烷更容易被大多数组织吸收和摄取。在研究期间清醒的狒狒未出现异常神经体征或行为。看来灵长类动物能从胃肠道吸收煤油,但吸收量非常小,不会引起明显的神经体征。

相似文献

1
Kerosene absorption in primates.灵长类动物对煤油的吸收。
J Pediatr. 1977 Sep;91(3):495-8. doi: 10.1016/s0022-3476(77)81334-6.
2
Kerosene intoxication: an experimental approach to the etiology of the CNS manifestations in primates.
J Pediatr. 1976 Jun;88(6):1037-40. doi: 10.1016/s0022-3476(76)81072-4.
3
[Pharmacokinetics of cyproterone acetate. A comparative study in humans and baboons].[醋酸环丙孕酮的药代动力学。人与狒狒的比较研究]
Int Z Klin Pharmakol Ther Toxikol. 1968 Jan;1(3):184-90.
4
[Intestinal resorption and excretion of alpha-acetyldigoxin-3H].[α-乙酰地高辛-3H的肠道吸收与排泄]
Wien Z Inn Med. 1973;54(7):324-31.
5
Experimental kerosene pneumonitis in primates: relevance to the therapeutic management of childhood poisoning.灵长类动物实验性煤油肺炎:与儿童中毒的治疗管理的相关性。
Clin Exp Pharmacol Physiol. 1976 Nov-Dec;3(6):539-44. doi: 10.1111/j.1440-1681.1976.tb00635.x.
6
[Metabolism and tissular distribution of d1-ephedrine 14C].[14C标记的d1-麻黄碱的代谢与组织分布]
Biochem Pharmacol. 1968 Nov;17(11):2319-31. doi: 10.1016/0006-2952(68)90040-3.
7
The physiological disposition of 14C-labeled 5-hydroxy-pyridine-2-carboxaldehyde thiosemicarbazone (NSC-107,392) in mice.
Biochem Med. 1972 Jun;6(3):282-93. doi: 10.1016/0006-2944(72)90050-6.
8
Tissue distribution of retinol and its metabolites after administration of double-labelled retinol.给予双标记视黄醇后视黄醇及其代谢产物的组织分布
Biochem J. 1975 Oct;152(1):99-104. doi: 10.1042/bj1520099.
9
[The tissular distribution of ephedrine and parahydroxyephedrine in the normal or sympathectomized rat by hydroxydopamine].[通过羟基多巴胺研究麻黄碱和对羟基麻黄碱在正常或交感神经切除大鼠体内的组织分布]
Biochem Pharmacol. 1972 May 1;21(9):1317-27. doi: 10.1016/0006-2952(72)90293-6.
10
3H-Corticosterone metabolism in the rat.大鼠体内的3H-皮质酮代谢
Acta Endocrinol (Copenh). 1969 Jul;61(3):483-93. doi: 10.1530/acta.0.0610483.

引用本文的文献

1
Effects of crude kerosene on testosterone levels, aggression and toxicity in rat.粗煤油对大鼠睾酮水平、攻击性及毒性的影响。
Toxicol Rep. 2014 Dec 1;2:175-183. doi: 10.1016/j.toxrep.2014.11.017. eCollection 2015.
2
Kerosene poisoning in children in Iraq.伊拉克儿童的煤油中毒情况。
Postgrad Med J. 1995 Jul;71(837):419-22. doi: 10.1136/pgmj.71.837.419.