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用于改善接受或未接受性别确认激素治疗的跨性别患者面部皮肤质量的注射美容治疗

Injectable Aesthetic Treatments for Improving Facial Skin Quality in Transgender Patients With or Without Gender-Affirming Hormone Therapy.

作者信息

Viscomi Bianca, Goldie Katherine, Kerscher Martina

机构信息

Bianca Viscomi Dermatologia Private Practice, São Paulo, Brazil.

Clinic 77, London, UK.

出版信息

J Cosmet Dermatol. 2025 Sep;24 Suppl 4(Suppl 4):e70318. doi: 10.1111/jocd.70318.

DOI:10.1111/jocd.70318
PMID:40847892
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12374562/
Abstract

BACKGROUND

Specialized medical care for transgender patients during the transition process can substantially improve mental and physical health for this population, due to the multitude of changes they may experience in both areas. Minimally invasive aesthetic procedures (MIPs) on the face can promote the anatomical changes and skin quality improvements necessary for gender affirmation, increasing gender congruence and, consequently, improving patients' quality of life. Given that gender-affirming hormone therapy (GAHT) impacts skin quality, MIPs may offer valuable complementary benefits during the transition process.

OBJECTIVE

Here we describe a novel treatment plan to improve skin quality in transgender patients who are or are not undergoing GAHT.

METHOD

The combination of incobotulinumtoxinA (Xeomin; Merz Pharmaceuticals GmbH, Frankfurt, Germany), calcium hydroxylapatite-carboxymethylcellulose (Radiesse; Merz North America Inc., Franksville, WI, USA), and Cohesive Polydensified Matrix hyaluronic acid with glycerol (CMP-HA20G, Belotero Revive; Anteis S.A., Plan-les-Ouates, Switzerland, a company of the Merz Aesthetics group) should be administered in a single session to improve skin quality. Photographs were taken at baseline and follow-up to assist with 3-dimensional reconstructions for evaluation of skin quality according to the four emergent perceptual categories (EPCs) defining skin quality.

OUTCOMES

EPC monitoring may help to guide MIP treatments, support future evaluation of treatment efficiency, and assist in delivering personalized gender-affirming care.

CONCLUSION

This new treatment plan for skin quality improvement offers gender-affirming care to the transgender community, based on clinical expertise.

摘要

背景

在转变过程中,为跨性别患者提供专业医疗护理可以显著改善这一群体的身心健康,因为他们在这两个方面可能会经历众多变化。面部微创美容手术(MIPs)可以促进性别确认所需的解剖结构变化和皮肤质量改善,增强性别一致性,从而提高患者的生活质量。鉴于性别确认激素疗法(GAHT)会影响皮肤质量,MIPs可能在转变过程中提供有价值的补充益处。

目的

在此,我们描述一种新的治疗方案,以改善正在或未接受GAHT的跨性别患者的皮肤质量。

方法

应在单次治疗中使用A型肉毒杆菌毒素(Xeomin;德国美兹制药有限公司,法兰克福)、羟基磷灰石 - 羧甲基纤维素(瑞得喜;美国威斯康星州弗兰克维尔市美兹北美公司)和含甘油的凝聚性多密度基质透明质酸(CMP - HA20G,贝洛特罗焕颜;瑞士普朗莱瓦泰市安蒂斯公司,美兹美学集团旗下公司)来改善皮肤质量。在基线和随访时拍照,以协助进行三维重建,根据定义皮肤质量的四个新兴感知类别(EPCs)评估皮肤质量。

结果

EPC监测可能有助于指导MIP治疗,支持未来对治疗效果的评估,并协助提供个性化的性别确认护理。

结论

这种改善皮肤质量的新治疗方案基于临床专业知识,为跨性别群体提供了性别确认护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/770306a8046e/JOCD-24-e70318-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/dd443a1d4d26/JOCD-24-e70318-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/5ef57968a2f6/JOCD-24-e70318-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/770306a8046e/JOCD-24-e70318-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/dd443a1d4d26/JOCD-24-e70318-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/5ef57968a2f6/JOCD-24-e70318-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/307a/12374562/770306a8046e/JOCD-24-e70318-g003.jpg

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本文引用的文献

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Calcium hydroxylapatite microspheres activate fibroblasts through direct contact to stimulate neocollagenesis.羟基磷灰石微球通过直接接触激活成纤维细胞,刺激新胶原生成。
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