Han Chong, Chen Kaichun, Cui Jiaxing, Cui Mingxiang, Shu Hu
School of Life Sciences, Guangzhou University, Guangzhou, 510006, China.
Guangdong Lianyi Aquatic Science and Technology Development Co., Ltd, Kaiping, 529300, China.
Mar Biotechnol (NY). 2025 Aug 23;27(5):129. doi: 10.1007/s10126-025-10510-4.
The zig-zag eel (Mastacembelus armatus) is an economically important aquaculture species in south China. Currently, the genome-wide association study (GWAS) for growth traits of zig-zag eel was first performed. A total of 175 zig-zag eels were measured for body height (BH), body length (BL), body weight (BW), body thickness (BT), head length (HL), and total length (TL) and genotyped using whole genome resequencing. After quality control, a total of 13,844,114 high-confidence SNPs were detected uniformly across 24 chromosomes. After GWAS, a total of 2, 1, 2, 2, 1, and 2 SNPs were significantly associated with BH, BL, BW, BT, HL, and TL traits, respectively. In addition, many candidate genes surrounding these SNPs have been shown to be closely associated with growth, including ppt1, cap1, lnr, and fgfr2. In all, these results lay a good foundation for exploring the molecular basis of growth regulation and molecular marker-assisted selection.
锯齿鳗（Mastacembelus armatus）是中国南方一种具有重要经济价值的水产养殖品种。目前，首次对锯齿鳗的生长性状进行了全基因组关联研究（GWAS）。共测量了175条锯齿鳗的体高（BH）、体长（BL）、体重（BW）、体厚（BT）、头长（HL）和全长（TL），并使用全基因组重测序进行基因分型。经过质量控制，在24条染色体上共均匀检测到13,844,114个高可信度单核苷酸多态性（SNP）。GWAS分析后，分别有2、1、2、2、1和2个SNP与BH、BL、BW、BT、HL和TL性状显著相关。此外，这些SNP周围的许多候选基因已被证明与生长密切相关，包括ppt1、cap1、lnr和fgfr2。总之，这些结果为探索生长调控的分子基础和分子标记辅助选择奠定了良好的基础。
