Shayestehpour Mohammad Amin, Gregersen Martin G, Saatvedt Ola, Bjelland Øystein, Molund Marius
Department of Orthopaedic Surgery, Østfold Hospital Trust, Grålum, Norway.
Department of ICT and Natural Sciences, Norwegian University of Science and Technology, Ålesund, Norway.
Foot Ankle Orthop. 2025 Aug 20;10(3):24730114251356497. doi: 10.1177/24730114251356497. eCollection 2025 Jul.
Deltoid ligament injuries occur in specific sequences during rotational ankle trauma, yet the current understanding of these sequences may be flawed. Computer modeling offers a new method for assessing ligament behavior under rotational injury mechanisms.
A biomechanical computer simulation model was developed using AnyBody Modeling Software to evaluate ligament strain in rotational ankle injuries. Experimental data from a cadaveric study involving 15 human ankle specimens subjected to various loading conditions were used to identify the model parameters. After parameter identification from uninjured cadaveric data, we simulated Supination-External Rotation (SER) stage 2-4b injury model by removing the corresponding ligaments. Validation was performed by comparing the model predictions against the biomechanical experimental data.
The computer model replicated experimental findings, with correlation coefficients ranging from 0.81 to 0.99 across all injury stages and loading conditions. Furthermore, tension in the deep posterior tibiotalar ligament (DPTTL) progressively increased from SER2 to SER4a but remained unchanged in the SER2 phase. The model effectively captured progressive ligament strain and changes in medial clear space during injury progression.
This study presents and validates an early-stage biomechanical simulation model for rotational ankle injuries, providing a novel tool for examining ligament biomechanics and injury mechanisms.
Our model offers insights that were previously unattainable through cadaveric or clinical studies by simulating ligament strain during injuries. This can assist in generating hypotheses, enhance injury detection, refine treatment strategies, and may challenge existing classification systems.
在踝关节旋转创伤过程中，三角韧带损伤按特定顺序发生，但目前对这些顺序的理解可能存在缺陷。计算机建模为评估旋转损伤机制下的韧带行为提供了一种新方法。
使用AnyBody建模软件开发了一种生物力学计算机模拟模型，以评估踝关节旋转损伤时的韧带应变。来自一项涉及15个人类踝关节标本并施加各种负荷条件的尸体研究的实验数据用于确定模型参数。从未受伤的尸体数据中确定参数后，我们通过移除相应韧带模拟旋后-外旋（SER）2-4b期损伤模型。通过将模型预测结果与生物力学实验数据进行比较来进行验证。
计算机模型复制了实验结果，在所有损伤阶段和负荷条件下，相关系数范围为0.81至0.99。此外，胫距后深层韧带（DPTTL）的张力从SER2逐渐增加到SER4a，但在SER2阶段保持不变。该模型有效地捕捉了损伤进展过程中韧带应变的逐渐变化以及内侧间隙的变化。
本研究提出并验证了一种用于踝关节旋转损伤的早期生物力学模拟模型，为研究韧带生物力学和损伤机制提供了一种新工具。
我们的模型通过模拟损伤过程中的韧带应变，提供了通过尸体或临床研究以前无法获得的见解。这有助于提出假设、加强损伤检测、完善治疗策略，并可能对现有的分类系统提出挑战。
