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铒铬:钇钪镓石榴石激光、蛋壳溶液及其组合对柠檬水致侵蚀性病变再矿化作用的评估

Evaluation of Effects of Er,Cr:YSGG Laser, Eggshell Solution, and Their Combination on the Remineralization of Erosive Lesion Caused by Lemonade.

作者信息

Dehghani Fatemeh, Haghgoo Roza, Asnaashari Mohammad, Dehghan Hossein

机构信息

Department of Orthodontics, Dental School, Hamadan University of Medical Sciences, Hamadan, Iran.

Department of Pediatric Dentistry, School of Dentistry, Shahed University, Tehran, Iran.

出版信息

J Lasers Med Sci. 2025 Jun 8;16:e15. doi: 10.34172/jlms.2025.15. eCollection 2025.

Abstract

Erosion is the loss of minerals by acids without the intervention of microorganisms. Complications caused by erosion make the use of therapeutic agents necessary. This study aims to survey the effects of the eggshell, the Er,Cr:YSGG laser, and their combination on the remineralization of erosive lesions caused by lemonade. The microhardness of 40 impacted third molar teeth was measured in this laboratory study. Then, the samples were subjected to an erosion challenge using a regular lemonade drink. After measuring microhardness, the samples were exposed to remineralizing materials: Er, Cr:YSG laser, eggshell, laser Er,Cr:YSGG, eggshell, and fluoride (positive control), and artificial saliva (negative control). Finally, data were analyzed via Kolmogorov-Smirnov, mixed-model analysis of variance (ANOVA), and LSD post hoc tests. The microhardness of permanent third molar teeth, which was reduced after using lemonade, increased significantly after laser application compared to fluoride and artificial saliva. No significant difference was observed between the five experimental groups while there were statistically significant differences between the three stages of the study. Moreover, there was a significant interaction between the groups and stages (group * stage). The SMH of fluoride, artificial saliva, and laser+solution groups did not significantly change in the three stages of the study whilst the SMH of laser and solution groups significantly changed in the three stages. The SMH of the laser group had the most increasing trend (between erosive and treatment stages), followed by laser+solution and solution groups. However, the change in the laser+solution group was not statistically noticeable. Based on the results of this study, the Er,Cr:YSGG laser alone can be effective in the remineralization of erosive lesions caused by lemonade.

摘要

酸蚀是指在没有微生物干预的情况下,矿物质被酸溶解流失。酸蚀引起的并发症使得使用治疗剂成为必要。本研究旨在调查蛋壳、铒铬:钇-钪-镓石榴石(Er,Cr:YSGG)激光及其联合应用对柠檬水所致侵蚀性病变再矿化的影响。在这项实验室研究中,测量了40颗阻生第三磨牙的显微硬度。然后,使用普通柠檬水饮料对样本进行酸蚀挑战。测量显微硬度后,将样本暴露于再矿化材料:Er,Cr:YSGG激光、蛋壳、Er,Cr:YSGG激光+蛋壳、氟化物(阳性对照)和人工唾液(阴性对照)。最后,通过柯尔莫哥洛夫-斯米尔诺夫检验、混合模型方差分析(ANOVA)和最小显著差事后检验对数据进行分析。使用柠檬水后硬度降低的恒牙第三磨牙,与氟化物和人工唾液相比,激光照射后显微硬度显著增加。五个实验组之间未观察到显著差异,而研究的三个阶段之间存在统计学显著差异。此外,组间和阶段之间存在显著交互作用(组*阶段)。在研究的三个阶段中,氟化物、人工唾液和激光+溶液组的表面显微硬度(SMH)没有显著变化,而激光和溶液组的SMH在三个阶段中有显著变化。激光组的SMH增加趋势最大(在侵蚀阶段和治疗阶段之间),其次是激光+溶液组和溶液组。然而,激光+溶液组的变化在统计学上不明显。基于本研究结果,单独使用Er,Cr:YSGG激光可有效促进柠檬水所致侵蚀性病变的再矿化。

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