de Marcos Lousa Carine
Centre for Plant Sciences, University of Leeds, Leeds LS29JT, UK.
School of Life sciences, University of Dundee, Dundee DD15EH, UK.
Extracell Vesicles Circ Nucl Acids. 2025 May 28;6(2):267-271. doi: 10.20517/evcna.2025.17. eCollection 2025.
Lignin is an important component of plant cell walls, providing structural support and defense. Despite extensive research, the mechanisms underlying the transport and polymerization of lignin precursors remain poorly understood. Kankaanpää . have explored the role of extracellular vesicles (EVs) in lignin biosynthesis in (Norway spruce). The authors identify key metabolites and enzymes involved in lignin biosynthesis and polymerization enriched in EVs from suspension cultures, suggesting a direct role for EVs in the transport and polymerization of lignin precursors. In addition, the presence of salicylic acid (SA) in EVs also highlights a novel synergy between lignin biosynthesis and plant defense mechanisms. This discovery challenges the traditional understanding of lignin biosynthesis by proposing that EVs act as mobile carriers, facilitating the localized polymerization of lignin in the cell wall. Further research is still needed to elucidate the exact nature of the EVs involved and the mechanisms of loading into and release from EVs. Nevertheless, these findings offer novel insights into the regulation of lignin biosynthesis and may have larger implications for agriculture and industrial applications.
木质素是植物细胞壁的重要组成部分，提供结构支撑和防御功能。尽管进行了广泛研究，但木质素前体的运输和聚合机制仍知之甚少。坎卡安佩等人研究了细胞外囊泡（EVs）在挪威云杉木质素生物合成中的作用。作者鉴定出悬浮培养物的EVs中富含参与木质素生物合成和聚合的关键代谢物和酶，这表明EVs在木质素前体的运输和聚合中起直接作用。此外，EVs中水杨酸（SA）的存在也凸显了木质素生物合成与植物防御机制之间的一种新协同作用。这一发现对木质素生物合成的传统认识提出了挑战，认为EVs作为移动载体，促进了细胞壁中木质素的局部聚合。仍需进一步研究以阐明所涉及的EVs的确切性质以及其装载到EVs中和从EVs中释放的机制。尽管如此，这些发现为木质素生物合成的调控提供了新见解，可能对农业和工业应用具有更广泛的意义。
