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用于肾脏CT血管造影方案的团注追踪技术的最佳触发阈值。

Optimal trigger threshold with the bolus-tracking technique for the renal CT angiography protocol.

作者信息

Asano Masashi, Noda Yoshifumi, Kawai Nobuyuki, Kaga Tetsuro, Omata Shingo, Takai Yukiko, Ito Akio, Iwata Takeshi, Miyoshi Toshiharu, Elhelaly Abdelazim Elsayed, Imai Hirohiko, Kato Hiroki, Matsuo Masayuki

机构信息

Department of Radiology, Gifu University, 1-1 Yanagido, Gifu, 501-1194, Japan.

Department of Radiology, Massachusetts General Hospital, 55 Fruit Street, White 270, Massachusetts, Boston, 02114, USA.

出版信息

Abdom Radiol (NY). 2025 Aug 25. doi: 10.1007/s00261-025-05158-6.

Abstract

OBJECTIVES

This study aimed to investigate the optimal trigger threshold for the renal CT angiography (CTA) protocol with the bolus-tracking technique.

METHODS

This retrospective study included patients suspected of having renal diseases and candidate kidney transplant donors who underwent renal CTA from July 2019 to August 2021. Renal arterial (RA) phase scanning was initiated using either one of the following two trigger thresholds: 50 HU (50-HU group; n = 42) and 100 HU (100-HU group; n = 63). A radiologist measured CT attenuations of the vasculature and renal parenchyma on RA phase images. Two radiologists classified RA phase images into appropriate RA-, late RA-, or corticomedullary (CM)-timing. Unpaired t- and Fisher's exact tests were conducted to assess differences in the CT attenuations and the proportion of categorical classifications between the two groups.

RESULTS

Overall, 105 patients (mean age: 59.8 years; 60 men) were included. CT attenuations of the aorta and renal arteries were comparable between the two groups (P = 0.38-0.95). CT attenuations of the renal cortex and renal vein were higher in the 100-HU group than in the 50-HU group (P = 0.006-0.04). The proportion of the appropriate RA-timing was higher, whereas that of the CM-timing was lower in the 50-HU group than in the 100-HU group (appropriate RA-, late RA-, and CM-timing: 78.6% vs. 50.8%, 19.0% vs. 34.9%, and 2.4% vs. 14.3%; P = 0.01 for reviewer 1 and 64.3% vs. 27.0%, 33.3% vs. 63.5%, and 2.4% vs. 9.5%; P < 0.001 for reviewer 2, respectively).

CONCLUSION

The trigger threshold of 50 HU provided a higher probability of obtaining appropriate RA-timing images than that of 100 HU in the renal CTA protocol with the bolus-tracking technique.

摘要

目的

本研究旨在探讨团注追踪技术在肾脏CT血管造影(CTA)方案中的最佳触发阈值。

方法

这项回顾性研究纳入了2019年7月至2021年8月期间接受肾脏CTA检查的疑似患有肾脏疾病的患者和潜在的肾移植供体。肾动脉(RA)期扫描采用以下两种触发阈值之一启动:50 HU(50-HU组;n = 42)和100 HU(100-HU组;n = 63)。一名放射科医生在RA期图像上测量血管和肾实质的CT衰减值。两名放射科医生将RA期图像分类为合适的RA期、延迟RA期或皮质髓质(CM)期。采用未配对t检验和Fisher精确检验来评估两组之间CT衰减值和分类比例的差异。

结果

总共纳入了105例患者(平均年龄:59.8岁;男性60例)。两组之间主动脉和肾动脉的CT衰减值相当(P = 0.38 - 0.95)。100-HU组的肾皮质和肾静脉的CT衰减值高于50-HU组(P = 0.006 - 0.04)。50-HU组中合适的RA期的比例更高,而CM期的比例低于100-HU组(合适的RA期、延迟RA期和CM期:78.6%对50.8%,19.0%对34.9%,2.4%对14.3%;审阅者1的P = 0.01,以及64.3%对27.0%,33.3%对63.5%,2.4%对9.5%;审阅者2的P < 0.001)。

结论

在采用团注追踪技术的肾脏CTA方案中,50 HU的触发阈值比100 HU更有可能获得合适的RA期图像。

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