Guard O, Graule A, Bellis-Lemerle F, Giroud M, Dumas R
Encephale. 1985 Sep-Oct;11(5):211-20.
The syndrome of interhemispheric disconnexion has been systematically researched in 10 cases of medial and posterior callosal tumours. The cases have been documented with CT Scann and two of them were anatomically verified. Two had a complete disconnexion syndrome; another, whose lesion was situated on the forceps major, had no sign of disconnexion. In the others, the semiology was proportional to the extent of the tumour, sometimes minimal and in this case, only corresponding to an extinction of the left ear in the dichotic test, which therefore appeared in our series as the most constant sign of a transfer-trouble. Among the other signs, left tactile anomia was found in two patients, left ideomotor apraxia in three, left visual anomia in five. Seven patients had a right constructional apraxia, which was bilateral in five of them. Left agraphia was noted in five patients, among which three had also a right hand dysgraphia, whose physiopathology is discussed. Tactile alexia was noted in three patients, two had a trouble of somesthesic information's transfer, one had a pure alexia (left occipital lesion plus splenium). Signs of hemispheric independence were uncommon: one patient presented a "foreign-hand sign".
对10例胼胝体中部和后部肿瘤患者的大脑半球间分离综合征进行了系统研究。这些病例均通过CT扫描记录在案,其中2例经解剖证实。2例出现完全性分离综合征;另1例病变位于胼胝体钳,未出现分离体征。其他病例中,症状学表现与肿瘤范围成正比,有时很轻微,在这种情况下,仅表现为双耳分听试验中左耳听力消失,因此在我们的系列研究中,这似乎是传导障碍最常见的体征。在其他体征中,2例患者出现左侧触觉失认,3例出现左侧观念运动性失用,5例出现左侧视觉失认。7例患者出现右侧结构性失用,其中5例为双侧性。5例患者出现左侧失写症,其中3例同时伴有右手书写障碍,并对其病理生理学进行了讨论。3例患者出现触觉失读症,2例存在躯体感觉信息传递障碍,1例为纯失读症(左侧枕叶病变加胼胝体压部)。半球独立性体征并不常见:1例患者出现“异己手征”。