Martins Clarice, Cavaleiro Rufo João, Fonseca Hélder, Padrão Ana, Baptista Liliana C, Santos Maria Paula, Sousa Miguel, Zacca Rodrigo, Silva José Pedro, Ribeiro Ana Isabel
Research Centre in Physical Activity, Health and Leisure; Faculty of Sport, University of Porto, Porto, Portugal.
Laboratory for Integrative and Translational Research in Population Health (ITR), Porto, Portugal.
BMJ Open. 2025 Aug 25;15(8):e097388. doi: 10.1136/bmjopen-2024-097388.
The MOVE-AIR study was designed to explore the moderating role of movement behaviours on the association between air pollutants and health outcomes in Portuguese children. Secondarily, it aims to characterise the settings (both indoor and outdoor) where children are exposed to air pollutants and to co-create solutions with participants to mitigate the exposure to air pollutants in children's daily life. This study aims to describe the MOVE-AIR study protocol in detail.
Data from 52 primary school children aged 9-11 years will be assessed for indoor and outdoor air pollutants (particulate matter (PM) and PM and carbon dioxide), geo-tracked for distinct settings (ie, home/school, indoor/outdoor) along the day, through an optical monitoring sensor with Global Positioning System incorporated. Health-related biological outcomes, such as interleukin-6, tumour necrosis factor alpha and oxidative parameters, including total antioxidant status and total oxidant status, will be evaluated and the Oxidative Stress Index will be calculated. Children's cardiopulmonary fitness will be assessed through the shuttle run test, and movement behaviours will be evaluated through accelerometers (wGT3X). Children's sex, age and parental socioeconomic status will be provided by parents through a questionnaire. The influence of movement behaviours in the link between pollution and health will be analysed through moderating regression models using process for SPSS R software (V.30.0.0). A subsample of class teachers, school leaders, parents and children will be invited to a co-creation process to create solutions to mitigate their daily exposure to air pollutants. The results will contribute to further understanding the moderating role of movement behaviours in the association between air pollution and health, adding a biological layer to the mechanistic links underlying these potential relationships that have not been explored in this target population. Finally, enhancing our comprehension of the living environments and contexts where children are more exposed to air pollution can help to cooperatively create solutions to mitigate their daily exposure to those harmful pollutants.
Ethical approval was granted by the Ethics Committee of the Faculty of Sports from the University of Porto (CEFADE 32-2023), and the study complies with the European Union (EU) General Data Protection Regulation under the supervision of the Data Protection Office of the Institute of Public Health, University of Porto (ISPUP).
“MOVE - AIR研究”旨在探讨运动行为对葡萄牙儿童空气污染物与健康结果之间关联的调节作用。其次,该研究旨在描述儿童接触空气污染物的环境(包括室内和室外),并与参与者共同制定解决方案,以减少儿童日常生活中空气污染物的暴露。本研究旨在详细描述“MOVE - AIR研究”方案。
将对52名9至11岁小学生的数据进行评估,通过内置全球定位系统的光学监测传感器,测定室内和室外空气污染物(颗粒物(PM)以及PM和二氧化碳),并在一天中对不同环境(即家庭/学校、室内/室外)进行地理追踪。将评估与健康相关的生物学指标,如白细胞介素 - 6、肿瘤坏死因子α以及氧化参数,包括总抗氧化状态和总氧化状态,并计算氧化应激指数。通过穿梭跑测试评估儿童的心肺适能,通过加速度计(wGT3X)评估运动行为。家长将通过问卷提供儿童的性别、年龄和父母社会经济地位。将使用SPSS R软件(版本30.0.0)的过程,通过调节回归模型分析运动行为在污染与健康之间联系中的影响。将邀请一个由班主任、学校领导、家长和儿童组成的子样本参与共同创造过程,以制定解决方案,减少他们日常接触空气污染物的情况。研究结果将有助于进一步理解运动行为在空气污染与健康关联中的调节作用,为这些潜在关系背后尚未在该目标人群中探索的机制联系增添生物学层面的内容。最后,加强我们对儿童更易接触空气污染的生活环境和背景的理解,有助于共同创造解决方案,减少他们日常接触这些有害污染物的情况。
该研究已获得波尔图大学体育学院伦理委员会(CEFADE 32 - 2023)的伦理批准,并且在波尔图大学公共卫生研究所(ISPUP)数据保护办公室的监督下,该研究符合欧盟(EU)通用数据保护条例。