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索马里摩加迪沙一家转诊医院中接受脊髓麻醉的剖宫产患者低血压的发生率及危险因素

Incidence and risk factors of hypotension in cesarean section patients under spinal anesthesia at a referral hospital in Mogadishu, Somalia.

作者信息

Barud Asha Abdullahi, Ali Ikran Abdulkadir, Hilowle Nasra Mohamud, Hassan Hiba Bashir, Osman Iftin Mohamed

机构信息

Department of Anesthesia, Mogadishu Somalia Turkey Recep Tayyip Erdoğan Training and Research Hospital, Mogadishu, Somalia.

Department of Neonatal Intensive Care Unit, Yardimeli Hospital, Mogadishu, Somalia.

出版信息

BMC Pregnancy Childbirth. 2025 Aug 25;25(1):883. doi: 10.1186/s12884-025-08024-x.

Abstract

BACKGROUND

Spinal anesthesia-induced hypotension is a common complication during cesarean sections, with significant implications for maternal and neonatal outcomes. However, data on the incidence and risk factors of hypotension in Africa, notably in Somalia, are limited. This study aimed to investigate the incidence and risk factors of hypotension in cesarean section patients under spinal anesthesia at a referral hospital in Mogadishu, Somalia.

METHODS

A cross-sectional study was conducted at a referral hospital in Mogadishu, Somalia, involving 320 patients who underwent cesarean section under spinal anesthesia using a systematic random sampling technique. Data on sociodemographic, medical history, and anesthetic characteristics were collected using a questionnaire. Descriptive statistics were used for frequencies and percentages. Chi-square tests and logistic regression were used to identify the risk factors associated with hypotension after spinal anesthesia at α = 0.05.

RESULTS

Among the 320 participants, the incidence of hypotension after spinal anesthesia during cesarean section was 78.1% (95%CI = 73.8-82.5]. In the multivariable model, five variables were found to be significantly associated with hypotension after spinal anesthesia in patients undergoing cesarean section: Mothers with BMI above 25 kg/m (AOR = 2.65, 95% CI = 1.39-5.04), mothers who had no hypertension during pregnancy (AOR = 6.00, 95% CI = 2.50-14.40), mothers who did not take preload IV fluid (AOR = 3.06, 95% CI = 1.22-7.66), mothers who did not take ephedrine medication (AOR = 8.84, 95% CI = 4.10-19.05), patients below 11 g/dl of preoperative hemoglobin (AOR = 2.52, 95% CI = 1.25-5.05).

CONCLUSIONS

This study found a high incidence of hypotension among mothers undergoing cesarean section under spinal anesthesia in Mogadishu. Significant risk factors included high BMI, low preoperative hemoglobin, lack of preload and absence of ephedrine use. Targeted interventions-such as preoperative risk screening, hemoglobin optimization, and prophylactic ephedrine use-are recommended to reduce the occurrence of spinal anesthesia-induced hypotension.

摘要

背景

脊髓麻醉诱导的低血压是剖宫产术中常见的并发症,对母婴结局有重大影响。然而,非洲尤其是索马里关于低血压发生率和危险因素的数据有限。本研究旨在调查索马里摩加迪沙一家转诊医院接受脊髓麻醉的剖宫产患者中低血压的发生率和危险因素。

方法

在索马里摩加迪沙的一家转诊医院进行了一项横断面研究,纳入320例采用系统随机抽样技术接受脊髓麻醉剖宫产的患者。使用问卷收集社会人口统计学、病史和麻醉特征数据。描述性统计用于频率和百分比。卡方检验和逻辑回归用于确定与脊髓麻醉后低血压相关的危险因素,α = 0.05。

结果

在320名参与者中,剖宫产术中脊髓麻醉后低血压的发生率为78.1%(95%CI = 73.8 - 82.5)。在多变量模型中,发现五个变量与接受剖宫产的患者脊髓麻醉后低血压显著相关:体重指数高于25kg/m²的母亲(调整后比值比[AOR] = 2.65,95%CI = 1.39 - 5.04)、孕期无高血压的母亲(AOR = 6.00,95%CI = 2.50 - 14.40)、未静脉输注预负荷液体的母亲(AOR = 3.06, 95%CI = 1.22 - 7.66)、未使用麻黄碱药物的母亲(AOR = 8.84, 95%CI = 4.10 - 19.05)、术前血红蛋白低于11g/dl的患者(AOR = 2.52, 95%CI = 1.25 - 5.05)。

结论

本研究发现摩加迪沙接受脊髓麻醉剖宫产的母亲中低血压发生率很高。重要的危险因素包括高体重指数、术前血红蛋白低、缺乏预负荷和未使用麻黄碱。建议采取针对性干预措施,如术前风险筛查、优化血红蛋白水平和预防性使用麻黄碱,以减少脊髓麻醉诱导的低血压的发生。

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本文引用的文献

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6
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Indian J Psychol Med. 2013 Apr;35(2):121-6. doi: 10.4103/0253-7176.116232.
9
Definitions of hypotension after spinal anaesthesia for caesarean section: literature search and application to parturients.
Acta Anaesthesiol Scand. 2010 Sep;54(8):909-21. doi: 10.1111/j.1399-6576.2010.02239.x. Epub 2010 Apr 23.
10
Purposeful selection of variables in logistic regression.
Source Code Biol Med. 2008 Dec 16;3:17. doi: 10.1186/1751-0473-3-17.

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