Storella R J, Riker W F, Baker T
Eur J Pharmacol. 1985 Nov 26;118(1-2):181-4. doi: 10.1016/0014-2999(85)90678-8.
Fast and slow neuromuscular systems in the rat were compared with respect to their sensitivity to d-tubocurarine (dTC). The fast tibialis anterior was more sensitive than the slow soleus to dTC-induced block of contractile tension when stimulated at either 0.2 or 1.0 Hz. These results in the rat contrast those made by others in the cat. Thus, relative drug sensitivities are not simply related to neuromuscular type.
就大鼠快慢神经肌肉系统对d-筒箭毒碱(dTC)的敏感性进行了比较。当以0.2Hz或1.0Hz的频率刺激时,快肌的胫骨前肌比慢肌的比目鱼肌对dTC诱导的收缩张力阻滞更为敏感。大鼠的这些结果与其他人在猫身上得到的结果形成对比。因此,相对药物敏感性并非简单地与神经肌肉类型相关。