Jose J G, Pitts D G
Exp Eye Res. 1985 Oct;41(4):545-63. doi: 10.1016/s0014-4835(85)80011-7.
Albino mice exposed to 1 X 10(-4) W cm-2 of UV radiation in the range 290-400 nm for 12 hr per day developed anterior lens opacities within 1-2 months after onset of the exposure. Histological changes demonstrated marked derangement of the lens epithelium. When the radiation was filtered with glass, eliminating radiation shorter than 320 nm, these opacities did not develop and the histology of the lenses was normal. We conclude that following chronic exposure, UV-B (290-320 nm) radiation is cataractogenic and acts via a mechanism involving the lens epithelium. UV-A (320-400 nm) does not appear to be cataractogenic, even with chronic exposure.
每天暴露于波长在290 - 400纳米、强度为1×10⁻⁴瓦/平方厘米的紫外线辐射下12小时的白化小鼠，在暴露开始后的1 - 2个月内出现了晶状体前囊混浊。组织学变化显示晶状体上皮有明显紊乱。当用玻璃过滤辐射，去除波长小于320纳米的辐射时，这些混浊未出现，晶状体的组织学正常。我们得出结论，长期暴露后，UV - B（290 - 320纳米）辐射具有致白内障作用，其作用机制涉及晶状体上皮。即使长期暴露，UV - A（320 - 400纳米）似乎也不具有致白内障作用。
