Sizova K V, Shestova G V, Predtechenskiĭ M B
Farmakol Toksikol. 1985 Nov-Dec;48(6):41-3.
Experiments on narcotized cats have shown that intravenous administration of armine in DL50 (0.2 mg/kg) decreases the pulmonary blood flow by 52%. The reduction of the pulmonary blood flow is accompanied by a drop of pressure in the femoral artery, development of bronchoconstriction, bradycardia and arterial hypoxemia. The pressure in the lung artery remains rather high. At the beginning of intoxication the decrease of the pulmonary blood flow correlates with bronchoconstriction in a greater degree than with other indicators and as the pathological process deepens, the reduction of the pulmonary blood flow gets closely connected with bradycardia.
对麻醉猫进行的实验表明，静脉注射DL50（0.2毫克/千克）的阿明会使肺血流量减少52%。肺血流量的减少伴随着股动脉压力下降、支气管收缩、心动过缓和动脉血氧不足。肺动脉压力仍然相当高。在中毒初期，肺血流量的减少与支气管收缩的关联程度大于与其他指标的关联，随着病理过程的加深，肺血流量的减少与心动过缓密切相关。
