[Synthesis and pharmacokinetic characteristics of 14CH3-polymethacryloyl lupinine--a heparin antagonist].

The quaternary salt of 1-14C-polymetacryloyl lupinine with a specific activity of 1 microCi/mM has been synthesized. It has been shown that intravenous injection of the polymer after heparin administration leads to uneven distribution of the label in the organs. The most intensive reduction of the label was observed in the kidneys. During 10 days, 85% of the label is eliminated from the body with urine and feces (76 and 9% respectively).