[去甲肾上腺素对皮肤温度感受器的作用机制]

[Mechanism of action of noradrenaline on cutaneous thermoreceptors].

作者信息

Kozyreva T V, Sindarovskaia I N

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1985 Nov;71(11):1344-50.

Abstract

The comparison of intradermal temperature, oxygen consumption and the rectal temperature with the skin cold-sensitive receptor responses to intraperitoneal and intraarterial noradrenaline injections shows that non-temperature changes following the increasing heat production or changing skin vessel tension are unrelated to augmentation of static receptors activity with rise of the noradrenaline concentration in the blood. It is possible that noradrenaline acts directly on thermoreceptors membrane. Apparently noradrenaline and sympathetic nervous system modulate the activity of the skin cold-sensitive receptors activity.

摘要

将皮内温度、氧耗量以及直肠温度与皮肤冷敏感受器对腹腔内和动脉内注射去甲肾上腺素的反应进行比较，结果表明，随着产热增加或皮肤血管张力变化而出现的非温度变化，与血液中去甲肾上腺素浓度升高时静态感受器活动的增强无关。去甲肾上腺素可能直接作用于温度感受器膜。显然，去甲肾上腺素和交感神经系统调节皮肤冷敏感受器的活动。