• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

通过探索不同的特征选择技术,基于监督模型检测多囊卵巢综合征与维生素D缺乏的关系。

Supervised model based polycystic ovarian syndrome detection in relation to vitamin d deficiency by exploring different feature selection techniques.

作者信息

Archana A, Sumathi V

机构信息

School of Electrical Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India.

Centre for E-Automation Technologies, School of Electrical Engineering, Vellore Institute of Technology, Chennai, Tamil Nadu, India.

出版信息

Sci Rep. 2025 Aug 26;15(1):31481. doi: 10.1038/s41598-025-14728-z.

DOI:10.1038/s41598-025-14728-z
PMID:40858748
Abstract

Due to urbanization and modern lifestyle, most of women in today's world are prone to Polycystic Ovarian Syndrome (PCOS), which is a hormonal disorder. Though the symptoms shown by this disease are often uncared, it seriously affects the reproductive health of women. Early detection of PCOS helps in managing several other attributes that are closely related to it. This article aims to study the impact of Vitamin D3 in PCOS and non-PCOS individuals. The goal is attained by building a tailored dataset with 1368 records and 43 attributes. Initially, the acquired dataset is pre-processed by handling missed values, outlier detection and data balancing by employing Probabilistic Principal Component Analysis (PPCA), Interquartile Range (IQR), Z-score standardization and SMOTE respectively. The significant features are selected by exploring different approaches such as filter based (Chi-Square, ANOVA), wrapper based (Electric Eel Foraging Optimization Algorithm) and embedded methods (LASSO, XGBoost). The selected features are utilized to train classifiers such as Random Forest (RF), k-Nearest Neighbour (k-NN), Decision Tree (DT) and Support Vector Machine (SVM). The experimental results show that the performance of EEFOA with RF prove the best accuracy rates of 98.8% with a F-measure of 98.19%. Explainable Artificial Intelligence (XAI) techniques such as SHAP and LIME are then employed to showcase the feature importance. It is observed that over 40% of PCOS patients are affected by deficiency and insufficiency of vitamin D3.

摘要

由于城市化和现代生活方式,当今世界的大多数女性都容易患多囊卵巢综合征(PCOS),这是一种激素紊乱疾病。尽管这种疾病表现出的症状常常被忽视,但它严重影响女性的生殖健康。早期发现多囊卵巢综合征有助于管理与之密切相关的其他几个方面。本文旨在研究维生素D3对多囊卵巢综合征患者和非多囊卵巢综合征患者的影响。通过构建一个包含1368条记录和43个属性的定制数据集来实现这一目标。最初,通过分别采用概率主成分分析(PPCA)、四分位距(IQR)、Z分数标准化和SMOTE来处理缺失值、异常值检测和数据平衡,对获取的数据集进行预处理。通过探索不同的方法,如基于过滤器的方法(卡方检验、方差分析)、基于包装器的方法(电鳗觅食优化算法)和嵌入式方法(套索回归、极端梯度提升)来选择显著特征。利用所选特征训练分类器,如随机森林(RF)、k近邻(k-NN)、决策树(DT)和支持向量机(SVM)。实验结果表明,电鳗觅食优化算法与随机森林相结合的性能证明了最佳准确率为98.8%,F值为98.19%。然后采用可解释人工智能(XAI)技术,如SHAP和LIME来展示特征重要性。据观察,超过40%的多囊卵巢综合征患者受到维生素D3缺乏和不足的影响。

相似文献

1
Supervised model based polycystic ovarian syndrome detection in relation to vitamin d deficiency by exploring different feature selection techniques.通过探索不同的特征选择技术,基于监督模型检测多囊卵巢综合征与维生素D缺乏的关系。
Sci Rep. 2025 Aug 26;15(1):31481. doi: 10.1038/s41598-025-14728-z.
2
Prescription of Controlled Substances: Benefits and Risks管制药品的处方:益处与风险
3
Aromatase inhibitors (letrozole) for subfertile women with polycystic ovary syndrome.芳香化酶抑制剂(来曲唑)用于多囊卵巢综合征的不孕女性。
Cochrane Database Syst Rev. 2018 May 24;5(5):CD010287. doi: 10.1002/14651858.CD010287.pub3.
4
Relations of Insulin Resistance, Body Weight, Vitamin D Deficiency, SHBG and Androgen Levels in PCOS Patients.多囊卵巢综合征患者胰岛素抵抗、体重、维生素D缺乏、性激素结合球蛋白及雄激素水平之间的关系
Biomedicines. 2025 Jul 23;13(8):1803. doi: 10.3390/biomedicines13081803.
5
Explainable AI-driven prediction of APE1 inhibitors: enhancing cancer therapy with machine learning models and feature importance analysis.可解释人工智能驱动的APE1抑制剂预测:利用机器学习模型和特征重要性分析增强癌症治疗
Mol Divers. 2025 Feb 21. doi: 10.1007/s11030-025-11133-6.
6
Facial emotion recognition accuracy in women with symptoms of polycystic ovary syndrome: Reduced fear and disgust perception.患有多囊卵巢综合征症状女性的面部情绪识别准确性:恐惧和厌恶感知能力降低。
Womens Health (Lond). 2025 Jan-Dec;21:17455057251359761. doi: 10.1177/17455057251359761. Epub 2025 Jul 28.
7
In vitro maturation in subfertile women with polycystic ovarian syndrome undergoing assisted reproduction.多囊卵巢综合征不孕妇女在辅助生殖过程中的体外成熟。
Cochrane Database Syst Rev. 2025 Feb 6;2(2):CD006606. doi: 10.1002/14651858.CD006606.pub5.
8
Aromatase inhibitors (letrozole) for ovulation induction in infertile women with polycystic ovary syndrome.芳香化酶抑制剂(来曲唑)在多囊卵巢综合征不孕妇女中的促排卵作用。
Cochrane Database Syst Rev. 2022 Sep 27;9(9):CD010287. doi: 10.1002/14651858.CD010287.pub4.
9
Systemic Inflammatory Response Syndrome全身炎症反应综合征
10
Management of urinary stones by experts in stone disease (ESD 2025).结石病专家对尿路结石的管理(2025年结石病专家共识)
Arch Ital Urol Androl. 2025 Jun 30;97(2):14085. doi: 10.4081/aiua.2025.14085.

本文引用的文献

1
EEG-based optimization of eye state classification using modified-BER metaheuristic algorithm.基于脑电图的眼状态分类优化:使用改进的BER元启发式算法
Sci Rep. 2024 Oct 18;14(1):24489. doi: 10.1038/s41598-024-74475-5.
2
Greylag goose optimization and multilayer perceptron for enhancing lung cancer classification.灰雁优化和多层感知机在肺癌分类中的应用。
Sci Rep. 2024 Oct 10;14(1):23784. doi: 10.1038/s41598-024-72013-x.
3
Orthopedic disease classification based on breadth-first search algorithm.基于广度优先搜索算法的骨科疾病分类。
Sci Rep. 2024 Oct 8;14(1):23368. doi: 10.1038/s41598-024-73559-6.
4
Polycystic ovary syndrome and its multidimensional impacts on women's mental health: A narrative review.多囊卵巢综合征及其对女性心理健康的多维影响:叙事性综述。
Medicine (Baltimore). 2024 Jun 21;103(25):e38647. doi: 10.1097/MD.0000000000038647.
5
Physiology of Vitamin D-Focusing on Disease Prevention.维生素 D 的生理学——关注疾病预防。
Nutrients. 2024 May 29;16(11):1666. doi: 10.3390/nu16111666.
6
Vitamin D deficiency, insulin resistance, and antimüllerian hormone level: a tale of trio in the expression of polycystic ovary syndrome.维生素 D 缺乏、胰岛素抵抗和抗苗勒管激素水平:多囊卵巢综合征表现中的三重奏。
F S Sci. 2024 Aug;5(3):252-264. doi: 10.1016/j.xfss.2024.06.002. Epub 2024 Jun 12.
7
Polycystic ovary syndrome.多囊卵巢综合征。
Nat Rev Dis Primers. 2024 Apr 18;10(1):27. doi: 10.1038/s41572-024-00511-3.
8
Predicting vitamin D deficiency using optimized random forest classifier.使用优化的随机森林分类器预测维生素 D 缺乏。
Clin Nutr ESPEN. 2024 Apr;60:1-10. doi: 10.1016/j.clnesp.2023.12.146. Epub 2023 Dec 28.
9
Designing Nutrition for Health-Incorporating Dietary By-Products into Poultry Feeds to Create Functional Foods with Insights into Health Benefits, Risks, Bioactive Compounds, Food Component Functionality and Safety Regulations.为健康设计营养——将膳食副产品纳入家禽饲料以创造功能性食品,并深入了解其健康益处、风险、生物活性化合物、食品成分功能及安全法规。
Foods. 2023 Nov 1;12(21):4001. doi: 10.3390/foods12214001.
10
Leveraging machine learning to evaluate factors influencing vitamin D insufficiency in SLE patients: A case study from southern Bangladesh.利用机器学习评估影响系统性红斑狼疮患者维生素D缺乏的因素:来自孟加拉国南部的案例研究。
PLOS Glob Public Health. 2023 Oct 31;3(10):e0002475. doi: 10.1371/journal.pgph.0002475. eCollection 2023.