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实践转变:转向对左侧和右侧急性恶性大肠梗阻(LBO)均采用先放置支架的方法。

Shifting practice: Moving to a stent first approach for both left and right sided acute malignant large bowel obstruction (LBO).

作者信息

Farrow Emily, Gardner Shona, Collin Neil, Pullyblank Anne

机构信息

North Bristol NHS Trust, Bristol, UK.

School of Medicine, Cardiff University, Cardiff, UK.

出版信息

Surg Endosc. 2025 Aug 26. doi: 10.1007/s00464-025-12035-2.

Abstract

BACKGROUND

To assess the safety and efficacy of a change to a stent first approach for malignant large bowel obstruction (LBO) in both left and right colon in a single centre over a 4-year period.

METHODS

This retrospective cohort study in an acute NHS Hospital Trust from 01/01/2019-31/12/2022 examines a change in practice from emergency surgery (ES) to colonic stenting for patients with both left and right sided acute malignant LBO. Co-primary outcomes were clinically successful bowel decompression following stenting and 30-day mortality. Secondary outcomes were length of stay, stent complications, stoma formation and minimally invasive surgery (MIS).

RESULTS

68 patients underwent colonic stenting, and 29 patients underwent primary ES for acute malignant LBO. Stenting achieved successful bowel decompression in 77.9%. 30-day mortality for those initially stented was 7.4% and for ES 6.9%. In palliative patients initially treated with stenting the stoma rate was lower (15.4 vs. 100.0%) with a reduced rate of open surgery (5.1 vs 87.5%) when compared to ES. In curative patients initially treated with stenting the stoma rate was lower (37.9 vs. 80.1%) with an increased rate of MIS (69.0 vs 19.0%), when compared to ES. 27.9% of patients underwent stenting proximal to the splenic flexure.

CONCLUSIONS

It is possible to offer colonic stenting to > 80% of patients presenting with acute malignant LBO despite not having a 24/7 rota. There was a reduced rate of stoma formation, open surgery and length of stay in both palliative and curative patients undergoing primary colonic stenting.

摘要

背景

评估在4年时间里,单一中心采用支架优先方法治疗左、右半结肠癌性大肠梗阻(LBO)的安全性和有效性。

方法

这项回顾性队列研究在一家急性国民保健服务医院信托机构中进行,研究时间为2019年1月1日至2022年12月31日,考察了针对左、右侧急性恶性LBO患者从急诊手术(ES)到结肠支架置入术的实践变化。共同主要结局是支架置入术后临床成功的肠道减压和30天死亡率。次要结局包括住院时间、支架并发症、造口形成和微创手术(MIS)。

结果

68例患者接受了结肠支架置入术,29例患者因急性恶性LBO接受了一期ES。支架置入术成功实现肠道减压的比例为77.9%。最初接受支架置入术患者的30天死亡率为7.4%,接受ES患者的为6.9%。与ES相比,最初接受支架置入术的姑息性患者造口率较低(15.4%对100.0%),开放手术率降低(5.1%对87.5%)。与ES相比,最初接受支架置入术的根治性患者造口率较低(37.9%对80.1%),MIS率增加(69.0%对19.0%)。27.9%的患者在脾曲近端接受了支架置入术。

结论

尽管没有全天候值班安排,但仍有可能为超过80%的急性恶性LBO患者提供结肠支架置入术。在接受一期结肠支架置入术的姑息性和根治性患者中,造口形成率、开放手术率和住院时间均有所降低。

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