Laha Poulami, Sutar Roshan F
Department of Psychiatry, AIIMS Bhopal, Bhopal, Madhya Pradesh, India.
Ind Psychiatry J. 2025 May-Aug;34(2):335-339. doi: 10.4103/ipj.ipj_60_25. Epub 2025 Jul 18.
Compulsive sexual behavior disorder (CSBD), trichotillomania (TTM), binge eating disorder (BED), and non-suicidal self-injury (NSSI) are classified in separate categories in the International Classification of Diseases, 11 Revision (ICD-11). This case series aims to explore these disorders' overlapping impulsive and compulsive features despite their shared phenomenology and comorbidity. It also discusses the insight, reward mechanisms, and associated neurobiological understanding of repetitive behaviors. In the end, it also highlights the potential role of glutamatergic medications in their treatment. Further research is warranted to explore the glutamatergic system's involvement and assess the efficacy of glutamate modulators across the impulsive-compulsive spectrum.
强迫性行为障碍(CSBD)、拔毛癖(TTM)、暴饮暴食症(BED)和非自杀性自伤行为(NSSI)在《国际疾病分类第11次修订版》(ICD - 11)中被分类在不同类别。本病例系列旨在探讨这些障碍尽管具有共同的现象学和共病情况,但仍存在重叠的冲动和强迫特征。它还讨论了对重复行为的洞察力、奖赏机制以及相关的神经生物学理解。最后,它还强调了谷氨酸能药物在其治疗中的潜在作用。有必要进行进一步研究,以探讨谷氨酸能系统的参与情况,并评估谷氨酸调节剂在整个冲动 - 强迫谱系中的疗效。