Gao Bocheng, Lin Yumeng, Zhang Huimin, Li Yulin, Gou Shuhua, Ma Peiling, Zhao Xueni, Zhou Yue, Chen Qian, Yuan Lan, Han Zhongyu, Yu Chang
Chengdu University of Traditional Chinese Medicine, Chengdu, China.
School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Front Med (Lausanne). 2025 Aug 8;12:1647629. doi: 10.3389/fmed.2025.1647629. eCollection 2025.
Liver cirrhosis is associated with serious complications of portal hypertension (PH), which ultimately causes variceal bleeding and ascites in a life-threatening manner. Non-invasive diagnostic techniques have evolved as an essential tool of early detection and management from a stand point of being dependent on invasive diagnostic techniques. This review summarises the most recent progress in noninvasive diagnostic possibilities in PH in liver cirrhosis in terms of its clinical use and future outlook. A literature review within the last decade and beyond revealed such studies which developed and utilised the indexing technique such as transient elastography, shear wave elastography and other more advanced imaging modalities. Non-invasive techniques which can be used to diagnose PH and monitor it have been made and have been shown to have the possibility of obviating invasive procedures. Given that these are noninvasive techniques, they represent valuable alternatives to invasive PH testing, and future work needs to be directed towards increasing accuracy of these tests and implementing these techniques into routine clinical practise.
肝硬化与门静脉高压（PH）的严重并发症相关，门静脉高压最终会以危及生命的方式导致静脉曲张出血和腹水。从依赖侵入性诊断技术的角度来看，非侵入性诊断技术已发展成为早期检测和管理的重要工具。本综述从临床应用和未来展望的角度总结了肝硬化门静脉高压非侵入性诊断可能性的最新进展。过去十年及更长时间的文献综述揭示了此类开发和利用如瞬时弹性成像、剪切波弹性成像等索引技术以及其他更先进成像方式的研究。已经开发出可用于诊断门静脉高压并对其进行监测的非侵入性技术，并且已证明这些技术有可能避免侵入性操作。鉴于这些是非侵入性技术，它们是侵入性门静脉高压检测的有价值替代方法，未来的工作需要致力于提高这些检测的准确性并将这些技术应用于常规临床实践。
