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腹腔镜侧方悬吊联合子宫骶韧带折叠缩短术与腹腔镜骶骨阴道固定术治疗盆腔器官脱垂的回顾性队列研究

Laparoscopic lateral suspension combined with uterosacral ligament folding and shortening versus laparoscopic sacrocolpopexy for the treatment of pelvic organ prolapse: a retrospective cohort study.

作者信息

Xiong Xiangpeng, Xia Leizhen, Mei Tong, Huang Jialv, Wang Ting, Zhang Yun, Wang Shuang, Luo Ye, Liu Haiping, Wang Liqun, Ai Xiaoyan

机构信息

Department of Gynecology, Jiangxi Maternal and Child Health Hospital, Nanchang, China.

Center for Reproductive Medicine, Jiangxi Maternal and Child Health Hospital, Nanchang, China.

出版信息

Front Med (Lausanne). 2025 Aug 8;12:1626735. doi: 10.3389/fmed.2025.1626735. eCollection 2025.

Abstract

BACKGROUND

Pelvic organ prolapse (POP) significantly impacts women's quality of life, with laparoscopic sacrocolpopexy (LSC) considered the gold standard for treatment. However, LSC carries risks of complications, prompting exploration of alternatives. This study compared the efficacy of Laparoscopic Lateral Suspension (LLS) combined with uterosacral ligament folding and shortening (LLS-ULFS) versus LSC for POP treatment.

OVERVIEW

A retrospective cohort study included 445 women with POP-Q stage ≥ II (LSC group: n=232; LLS-ULFS group: n=213). Surgical outcomes, complications, and patient-reported outcomes were evaluated over a 2-year follow-up period at Jiangxi Maternal and Child Health Hospital.

RESULTS

Both groups achieved high anatomical success rates (LSC vs. LLS-ULFS): apical (96.98% vs. 94.84%), anterior (94.40% vs. 96.24%), and posterior (96.12% vs. 94.37%) compartments (all P>0.05). The LLS-ULFS group demonstrated superior perioperative outcomes: shorter operation time (85 vs. 105 min, P<0.001), reduced blood loss (40 vs. 50 ml, P<0.001), and lower pain scores (VAS: 4 vs. 4, P<0.001). Long-term follow-up showed significantly better patient-reported outcomes in the LLS-ULFS group for PFDI-20, POPDI-6, CRADI-8, and PISQ-12 scores (all P<0.05), indicating improved quality of life and sexual function. Complication rates were comparable (P>0.05).

DISCUSSION

LLS-ULFS achieves anatomical success equivalent to LSC while offering advantages in operative efficiency and recovery. The technique's avoidance of presacral dissection likely contributes to reduced pain and complications.

CONCLUSION

LLS-ULFS is a viable alternative to LSC, providing comparable anatomical correction with superior perioperative outcomes and enhanced quality of life. Its efficacy supports broader clinical adoption for POP management.

摘要

背景

盆腔器官脱垂(POP)对女性生活质量有显著影响,腹腔镜骶骨阴道固定术(LSC)被认为是治疗的金标准。然而,LSC存在并发症风险,促使人们探索替代方法。本研究比较了腹腔镜侧方悬吊术(LLS)联合子宫骶韧带折叠缩短术(LLS - ULFS)与LSC治疗POP的疗效。

概述

一项回顾性队列研究纳入了445例POP - Q分期≥II期的女性(LSC组:n = 232;LLS - ULFS组:n = 213)。在江西省妇幼保健院进行了为期2年的随访,评估手术结果、并发症及患者报告的结局。

结果

两组均取得了较高的解剖学成功率(LSC组与LLS - ULFS组):顶端(96.98%对94.84%)、前部(94.40%对96.24%)和后部(96.12%对94.37%)腔室(所有P>0.05)。LLS - ULFS组在围手术期结局方面表现更优:手术时间更短(85对105分钟,P<0.001)、失血更少(40对50毫升,P<0.001)、疼痛评分更低(视觉模拟评分法:4对4,P<0.001)。长期随访显示,LLS - ULFS组在PFDI - 20、POPDI - 6、CRADI - 8和PISQ - 12评分方面患者报告的结局明显更好(所有P<0.05),表明生活质量和性功能得到改善。并发症发生率相当(P>0.05)。

讨论

LLS - ULFS在解剖学上取得了与LSC相当的成功,同时在手术效率和恢复方面具有优势。该技术避免了骶前解剖,可能有助于减轻疼痛和减少并发症。

结论

LLS - ULFS是LSC的一种可行替代方法,在解剖学矫正方面相当,围手术期结局更优,生活质量提高。其疗效支持在POP管理中更广泛地应用于临床。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df9f/12370751/bc4a6c97c18b/fmed-12-1626735-g001.jpg

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