Noda Kazuki, Sunamura Shinichiro, Suzuki Masahiro, Shibutani Kazuyuki, Tanita Atsushi, Ogata Tsuyoshi, Takii Toru, Ushigome Ryoichi, Wakayama Yuji, Kumagai Koji, Namiuchi Shigeto
Department of Cardiology Sendai City Medical Center Sendai Open Hospital Sendai Japan.
Ushigome Clinic Sendai Japan.
J Arrhythm. 2025 Aug 21;41(4):e70179. doi: 10.1002/joa3.70179. eCollection 2025 Aug.
A left atrial (LA) posterior wall isolation (PWI) is a common additional strategy for persistent atrial fibrillation (PeAF) ablation; yet its impact on the LA function remains unclear.
This study aimed to evaluate the effect of the PWI on the LA contractile function using intracardiac echocardiography (ICE).
Patients who underwent catheter ablation of PeAF were categorized into extensive encircling pulmonary vein isolation (EEPVI) and PWI groups. The LA contractile function was assessed using the PV reversal wave (PVa) velocity measured by ICE.
No significant difference in the PVa velocity was observed between the EEPVI and PWI group. The EEPVI group patients were categorized into four groups based on scar extent: low-scar, anterior wall (AW)-scar-only, posterior wall (PW)-scar-only, and both walls-scarred. Compared to the low-scar group, the both walls-scar group had significantly lower PVa velocities; though no significant difference was found compared to the PW-scar-only group. The PVa velocity had a significant correlation with the AW scar. Furthermore, all patients enrolled in this study were also categorized into four groups based on the scar presence, similar to the previous study. Compared with the low-scar group, the PVa velocities were significantly lower in the AW-scar-only and both walls-scar groups; however, there was no significant difference in the PW-scar-only group. The PVa velocity was significantly correlated with the AW scar.
An LA PWI did not significantly impair the LA contractile function. AW scarring appeared to have a greater impact on the LA contractility than the PWI or scarring.
左心房后壁隔离术(PWI)是持续性心房颤动(PeAF)消融术中常用的附加策略;但其对左心房功能的影响尚不清楚。
本研究旨在使用心内超声心动图(ICE)评估PWI对左心房收缩功能的影响。
将接受PeAF导管消融术的患者分为广泛环绕肺静脉隔离术(EEPVI)组和PWI组。使用ICE测量的肺静脉逆向波(PVa)速度评估左心房收缩功能。
EEPVI组和PWI组之间PVa速度无显著差异。EEPVI组患者根据瘢痕范围分为四组:低瘢痕组、仅前壁(AW)瘢痕组、仅后壁(PW)瘢痕组和双壁瘢痕组。与低瘢痕组相比,双壁瘢痕组的PVa速度显著降低;但与仅PW瘢痕组相比无显著差异。PVa速度与AW瘢痕显著相关。此外,本研究纳入的所有患者也根据瘢痕情况分为四组,与先前研究类似。与低瘢痕组相比,仅AW瘢痕组和双壁瘢痕组的PVa速度显著降低;然而,仅PW瘢痕组无显著差异。PVa速度与AW瘢痕显著相关。
左心房PWI并未显著损害左心房收缩功能。AW瘢痕对左心房收缩性的影响似乎比PWI或瘢痕更大。