Lan Xiaohe, Huang Yajing, Lu Yantong, Chen Yuqin, Wang Changjun
Institute of Geriatrics, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Guangzhou University of Chinese Medicine, Guangzhou, China.
Int J Surg Protoc. 2025 Apr 21;29(2):52-56. doi: 10.1097/SP9.0000000000000044. eCollection 2025 Jun.
Musculoskeletal pain is one of the most common conditions in the general population, causing a variety of adverse effects. In addition to pharmacological treatments, the use of acupuncture has increased in recent decades and has shown satisfactory effects. However, the effect of catgut implantation at acupoint (CIA), a specific form of acupuncture, on the treatment of musculoskeletal pain has remained uncertain. Therefore, the aim of this study is to access whether CIA is effective and safe compared with other treatments for musculoskeletal pain.
Nine electronic databases, including six English databases (e.g. Medline and Embase) and three Chinese databases (e.g. CNKI and Wanfang database) will be searched from the inception to 1 May 2024. Only randomized controlled trials evaluating the effect of CIA for musculoskeletal pain in adults will be included. Two reviewers will independently perform the literature screening, data extraction and quality assessment. Primary outcome is pain symptoms assessed by any pain scale (e.g. visual analogue scale). Pooled results will be calculated using a fixed-effects model if heterogeneity is not significant ( < 50%), otherwise, a random-effects model will be used. Several subgroup analyses and sensitivity analyses will be performed. All statistical analyses will be conducted using STATA 18.0.
A synthesis of the current evidence on the effect of CIA on the treatment of musculoskeletal pain will be published in a peer-reviewed journal.
This study will provide high quality evidence of the effect of CIA on the treatment of musculoskeletal pain.
肌肉骨骼疼痛是普通人群中最常见的病症之一，会引发多种不良影响。除药物治疗外，近几十年来针灸的使用有所增加，且已显示出令人满意的效果。然而，穴位埋线（CIA）作为一种特殊形式的针灸，其对肌肉骨骼疼痛治疗的效果仍不明确。因此，本研究的目的是评估与其他治疗肌肉骨骼疼痛的方法相比，穴位埋线是否有效且安全。
将检索九个电子数据库，包括六个英文数据库（如Medline和Embase）和三个中文数据库（如中国知网和万方数据库），检索时间从建库至2024年5月1日。仅纳入评估穴位埋线对成人肌肉骨骼疼痛治疗效果的随机对照试验。两名评价者将独立进行文献筛选、数据提取和质量评估。主要结局是通过任何疼痛量表（如视觉模拟量表）评估的疼痛症状。如果异质性不显著（I²<50%），将使用固定效应模型计算合并结果，否则将使用随机效应模型。将进行多项亚组分析和敏感性分析。所有统计分析将使用STATA 18.0进行。
关于穴位埋线对肌肉骨骼疼痛治疗效果的当前证据综合将发表在同行评审期刊上。
本研究将提供穴位埋线对肌肉骨骼疼痛治疗效果的高质量证据。
