Johri Prishay, Rani Rohan, Spevak Christopher, Sotomayor Claudia, Cornish Nicole, De Marchi Lorenzo, Wain Harold, Roberts Allen
Anesthesiology, Georgetown University School of Medicine, Washington, USA.
Bioethics, Georgetown University Medical Center, Washington, USA.
Cureus. 2025 Jul 25;17(7):e88765. doi: 10.7759/cureus.88765. eCollection 2025 Jul.
Organ procurement procedures have evolved significantly over the past decade, resulting in new moral uncertainties. The dead donor rule (DDR), a foundational principle, mandates that organ procurement occurs only after death is confirmed. However, developments such as donation after circulatory death (DCD) and normothermic regional perfusion (NRP) have raised ethical issues, creating moral distress and moral injury among anesthesiologists. This review highlights the recent changes in the organ procurement processes and the potential impact on anesthesiologists and also discusses the strategies to prevent and manage moral distress. A narrative review was conducted using a structured search strategy across Ovid MEDLINE, Embase, and Web of Science. The search included the terms "anesthesiology", "moral distress", "dead donor rule", "brain death", and "normothermic regional perfusion". Of the 77 identified articles, 18 met inclusion criteria focusing on the ethical, psychological, and educational aspects of the anesthesiologist's role in organ procurement. The increasing use of novel organ procurement techniques such as NRP after DCD may result in moral distress among anesthesiologists. While the literature on moral distress continues to expand in the healthcare field, more needs to be written on this topic with anesthesiologists involved in organ procurement. Anesthesiologists are participating in novel organ procurement techniques with minimal control of decision-making. As a result, moral distress may occur with negative consequences. Solutions to the identification and prevention of moral distress with organ procurement include expanded ethics education, peer and mentor support, and institutional support. Addressing these issues can empower anesthesiologists to navigate complex scenarios, mitigating moral distress and increasing wellness and patient safety.
在过去十年中,器官获取程序发生了显著演变,引发了新的道德不确定性。作为一项基本原则的死亡捐献者规则(DDR)规定,只有在确认死亡后才能进行器官获取。然而,诸如心脏死亡后捐献(DCD)和常温区域灌注(NRP)等进展引发了伦理问题,给麻醉医生带来了道德困扰和道德伤害。本综述强调了器官获取过程中的近期变化及其对麻醉医生的潜在影响,并讨论了预防和处理道德困扰的策略。我们使用结构化检索策略在Ovid MEDLINE、Embase和科学网进行了叙述性综述。检索词包括“麻醉学”“道德困扰”“死亡捐献者规则”“脑死亡”和“常温区域灌注”。在77篇已识别的文章中,18篇符合纳入标准,重点关注麻醉医生在器官获取中角色的伦理、心理和教育方面。DCD后越来越多地使用诸如NRP等新型器官获取技术可能会给麻醉医生带来道德困扰。虽然医疗领域关于道德困扰的文献在不断增加,但对于参与器官获取的麻醉医生而言,关于这一主题仍有更多内容需要撰写。麻醉医生在对决策几乎没有控制权的情况下参与新型器官获取技术。因此,可能会出现道德困扰并产生负面后果。识别和预防器官获取中道德困扰的解决方案包括扩大伦理教育、同行和导师支持以及机构支持。解决这些问题可以使麻醉医生有能力应对复杂情况,减轻道德困扰,提高健康水平和患者安全。