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成人型胰腺母细胞瘤

Adult-Onset Pancreatoblastoma.

作者信息

Gonzales Thomas, Mahmood Sultan, Khan Saifur R, Singhi Aatur

机构信息

Department of Internal Medicine, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Department of Gastroenterology, University of Pittsburgh School of Medicine, Pittsburgh, PA.

出版信息

ACG Case Rep J. 2025 Aug 25;12(8):e01814. doi: 10.14309/crj.0000000000001814. eCollection 2025 Aug.

Abstract

Pancreatoblastoma (PB), an extremely rare malignancy of the pancreatic tissue, comprises less than 1% of all pancreatic tumors. Owing to the rarity of the malignancy and the potential for multiple differential diagnoses, adult-onset PB can be challenging to diagnose. The hallmark characteristic in diagnosing adult PB is found histologically. In approximately 90% of cases, squamous corpuscles are observed. We present the case of a patient diagnosed with adult-onset PB, who presented with key clinical and pathological features, as well as rarer characteristics, associated with the malignancy.

摘要

胰腺母细胞瘤(PB)是一种极其罕见的胰腺组织恶性肿瘤,占所有胰腺肿瘤的比例不到1%。由于这种恶性肿瘤罕见且存在多种鉴别诊断的可能性,成人发病的PB诊断具有挑战性。诊断成人PB的标志性特征可通过组织学检查发现。在大约90%的病例中,可以观察到鳞状小体。我们报告一例诊断为成人发病PB的患者,该患者呈现出与这种恶性肿瘤相关的关键临床和病理特征以及较为罕见的特征。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c6c2/12377294/d71a24efca4c/ac9-12-e01814-g001.jpg

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