硫胺素营养状况评估。红细胞转酮醇酶活性、刺激后的红细胞转酮醇酶活性及硫胺素焦磷酸效应的评估。
Assessment of the thiamine nutritional status. An evaluation of erythrocyte transketolase activity, the stimulated erythrocyte transketolase activity, and the thiamine pyrophosphate effect.
作者信息
Graudal N, Torp-Pedersen K, Hanel H, Kristensen M, Thomsen A C, Nørgård G
出版信息
Int J Vitam Nutr Res. 1985;55(4):399-403.
The most widely accepted approach to estimation of thiamine nutrition has been the measurement of the erythrocyte transketolase activity (ETKA), the ETKA stimulated in vitro with thiamine pyrophosphate (TPP) (which is suggested to be designated ETKAS) and the percentage increase of ETKA after stimulation with TPP in vitro, called the thiamine pyrophosphate effect (TPPE). In spite of 30 years of experience in the determination of these variables doubtfulness still exists of how to assess them. On the basis of a study of a group of alcoholics and a group of non-alcoholics a system of evaluation of ETKA, ETKAS and TPPE is proposed.
评估硫胺素营养状况最广泛接受的方法是测量红细胞转酮醇酶活性（ETKA）、用焦磷酸硫胺素（TPP）在体外刺激后的ETKA（建议称为ETKAS）以及体外TPP刺激后ETKA的增加百分比，即焦磷酸硫胺素效应（TPPE）。尽管在测定这些变量方面已有30年的经验，但对于如何评估它们仍存在疑问。基于对一组酗酒者和一组非酗酒者的研究，提出了一种评估ETKA、ETKAS和TPPE的系统。
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