Park Crystal L, Gnall Katherine E, Salafia Caroline, Bellizzi Keith M
Department of Psychological Sciences, University of Connecticut, Storrs, CT 06269, USA.
Department of Human Development and Family Sciences, University of Connecticut, Storrs, CT 06269, USA.
Curr Oncol. 2025 Jul 26;32(8):420. doi: 10.3390/curroncol32080420.
Social adversity is linked to poorer physical health in breast cancer survivors, highlighting the urgency of addressing health equity. Simultaneously, identifying individual-level factors that mitigate these effects may provide more immediate relief for survivors. This study examined whether four modifiable psychosocial factors-emotion dysregulation, physical activity, sleep disturbance, and social support-moderate the relationship between place-based social adversity and physical health in 255 breast cancer survivors (Mage = 56.03, 74.5% non-Hispanic White) within six months post-treatment. Linear regression analyses with 5000 bootstrapped estimates revealed that sleep disturbance significantly moderated the relationship between place-based social adversity and physical health (B = -0.014, SE = 0.001, bootstrapped 95% CI = -0.027, -0.001). Specifically, greater place-based social adversity was associated with poorer physical health at high levels of sleep disturbance (B = -0.22, = 0.004), but not at low (B = 0.01, = 0.94) or average (B = -0.10, = 0.07) levels. Emotion dysregulation, physical activity, and social support did not moderate this relationship. Findings suggest that improving sleep quality may buffer the negative impact of social adversity on physical health, identifying sleep as a potential target for interventions aimed at reducing disparities among breast cancer survivors.
社会逆境与乳腺癌幸存者较差的身体健康状况相关，这凸显了解决健康公平问题的紧迫性。同时，识别能够减轻这些影响的个体层面因素可能会为幸存者提供更直接的缓解。本研究调查了情绪失调、体育活动、睡眠障碍和社会支持这四个可改变的心理社会因素是否会调节255名乳腺癌幸存者（年龄中位数 = 56.03岁，74.5%为非西班牙裔白人）在治疗后六个月内基于居住地的社会逆境与身体健康之间的关系。采用5000次自抽样估计的线性回归分析表明，睡眠障碍显著调节了基于居住地的社会逆境与身体健康之间的关系（B = -0.014，标准误 = 0.001，自抽样95%置信区间 = -0.027，-0.001）。具体而言，在睡眠障碍程度较高时，基于居住地的社会逆境越大，身体健康状况越差（B = -0.22，P = 0.004），但在睡眠障碍程度较低（B = 0.01，P = 0.94）或中等（B = -0.10，P = 0.07）时并非如此。情绪失调、体育活动和社会支持并未调节这种关系。研究结果表明，改善睡眠质量可能会缓冲社会逆境对身体健康的负面影响，这表明睡眠是旨在减少乳腺癌幸存者之间差异的干预措施的一个潜在目标。
