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初次全髋关节置换中短柄与标准柄的比较:一项使用血清标志物的围手术期前瞻性侵入性研究。

Short Stem vs. Standard Stem in Primary Total Hip Replacement: A Perioperative Prospective Invasiveness Study with Serum Markers.

作者信息

Senarighi Marco, Ciccullo Carlo, de Berardinis Luca, Meco Leonard, Giampaolini Nicola, Aspriello Simone Domenico, Farinelli Luca, Gigante Antonio Pompilio

机构信息

Maria Cecilia Hospital-GVM Care & Research, 48033 Cotignola, Italy.

Clinical Ortopaedics, Department of Clinical and Molecular Sciences, Politecnica University of Marche, 60126 Ancona, Italy.

出版信息

Diseases. 2025 Jul 23;13(8):233. doi: 10.3390/diseases13080233.

Abstract

BACKGROUND

Total hip arthroplasty (THA) is a well-established surgical procedure for end-stage hip arthrosis. Innovations such as minimally invasive approaches and new technologies have improved outcomes and reduced invasiveness. The introduction of short-stem prostheses, which offer potential benefits in bone preservation, has been a significant development in recent years. This prospective case series study aims to compare invasiveness of the short-stem (SS) and conventional-stem (CS) prostheses in THA with a posterolateral approach (PLA) by assessing perioperative serum markers.

METHODS

A prospective case series was conducted involving consecutive patients who underwent primary THA from January 2022 to December 2023. Demographics and preoperative, postoperative day 1 (POD1), and postoperative day 2 (POD2) serum levels of C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), procalcitonin (PCT), and white blood cells (WBCs) were measured.

RESULTS

The study included 21 patients with CS and 19 with SS, with no significant differences between groups in demographic. No statistically significant differences were found in serum markers between SS and CS groups at any time point. Both groups showed significant increases in ESR, CRP, and PCT from preoperative levels to POD2 ( < 0.001), while WBC values increased from preoperative to POD1 but decreased between POD1 and POD2.

CONCLUSION

The short-stem prosthesis does not exhibit significantly different perioperative serum marker profiles compared to the conventional stem, suggesting similar levels of surgical invasiveness between the two implants. Further studies with larger sample sizes are needed to validate these findings and explore other aspects of short-stem THA.

摘要

背景

全髋关节置换术(THA)是治疗终末期髋关节骨关节炎的一种成熟手术方法。诸如微创入路和新技术等创新改善了手术效果并降低了创伤性。短柄假体的引入在保留骨量方面具有潜在益处,是近年来的一项重大进展。本前瞻性病例系列研究旨在通过评估围手术期血清标志物,比较采用后外侧入路(PLA)的THA中短柄(SS)和传统柄(CS)假体的创伤性。

方法

进行了一项前瞻性病例系列研究,纳入2022年1月至2023年12月连续接受初次THA的患者。测量人口统计学数据以及术前、术后第1天(POD1)和术后第2天(POD2)的血清C反应蛋白(CRP)、红细胞沉降率(ESR)、降钙素原(PCT)和白细胞(WBC)水平。

结果

该研究包括21例使用CS假体和19例使用SS假体的患者,两组在人口统计学方面无显著差异。在任何时间点,SS组和CS组之间的血清标志物均未发现统计学上的显著差异。两组的ESR、CRP和PCT从术前水平到POD2均显著升高(<0.001),而WBC值从术前到POD1升高,但在POD1和POD2之间下降。

结论

与传统柄假体相比,短柄假体在围手术期血清标志物方面没有显著差异,表明两种植入物的手术创伤程度相似。需要更大样本量的进一步研究来验证这些发现并探索短柄THA的其他方面。

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