Lozada-Ramos Heiler, Daza-Arana Jorge Enrique
Medicine Program, Faculty of Health, Universidad Santiago de Cali, Palmira 763532, Colombia.
Doctoral Program in Infectious Diseases, Universidad de Santander-UDES, Bucaramanga 680003, Colombia.
Infect Dis Rep. 2025 Aug 6;17(4):96. doi: 10.3390/idr17040096.
Scrofuloderma, a cutaneous manifestation of tuberculosis, is a rare but clinically significant form of mycobacterial infection. It typically results from the local spread of Mycobacterium tuberculosis from an infected lymph node or bone area to the overlying skin. This disease is mainly characterized by chronic granulomatous inflammation, leading to skin ulcers and abscesses. Due to its nonspecific clinical presentation, scrofuloderma can mimic various dermatological conditions, making its diagnosis particularly challenging. This case report presents the clinical course of a patient who was positive for the Human Immunodeficiency Virus (HIV) with a diagnosis of scrofuloderma, managed at a tertiary healthcare center, with follow-up before and after treatment. A literature review was also made, highlighting the importance of maintaining a high index of clinical suspicion and utilizing appropriate diagnostic methods to ensure timely diagnosis.
瘰疬性皮肤结核是结核病的一种皮肤表现，是一种罕见但具有临床意义的分枝杆菌感染形式。它通常是由结核分枝杆菌从感染的淋巴结或骨区域局部扩散到覆盖的皮肤引起的。这种疾病主要以慢性肉芽肿性炎症为特征，导致皮肤溃疡和脓肿。由于其临床表现不具特异性，瘰疬性皮肤结核可模仿各种皮肤病，这使得其诊断极具挑战性。本病例报告介绍了一名人类免疫缺陷病毒（HIV）检测呈阳性且诊断为瘰疬性皮肤结核的患者的临床病程，该患者在三级医疗中心接受治疗，并在治疗前后进行了随访。还进行了文献综述，强调了保持高度临床怀疑指数以及采用适当诊断方法以确保及时诊断的重要性。
