Raju Manikandan, Perrone Marco Alfonso, Alashram Anas R, Iellamo Ferdinando
Department of Neurorehabilitation Sciences, Casa-di-Cura Igea, 20144 Milan, Italy.
Department of Human Neuroscience, Sapienza University of Rome, 00185 Rome, Italy.
J Cardiovasc Dev Dis. 2025 Aug 19;12(8):317. doi: 10.3390/jcdd12080317.
The role of blood pressure variability (BPV) as an important marker of cardiovascular (CV) health, specifically its relationship with arterial stiffness and left ventricular remodeling in patients with hypertension, was investigated. This review aimed to elucidate the intricate relationship between BPV, arterial stiffness, and cardiac remodeling. BPV, as both a risk factor and a target of treatment, was also evaluated. The results point to the pivotal role of BPV in cardiovascular events, serving as an independent factor contributing to arterial stiffness and adverse left ventricular remodeling. The article concludes that BPV is a modifiable risk factor and that there is a need for an intervention in specific regions. BPV is a therapy target that is significant in the treatment of hypertension. The optimization of risk and prevention needs a multidisciplinary approach involving rehabilitation therapy, which will improve cardiovascular conditions and patient outcomes.
研究了血压变异性(BPV)作为心血管(CV)健康重要标志物的作用,特别是其与高血压患者动脉僵硬度和左心室重构的关系。本综述旨在阐明BPV、动脉僵硬度和心脏重构之间的复杂关系。还评估了BPV作为危险因素和治疗靶点的情况。结果表明BPV在心血管事件中起关键作用,是导致动脉僵硬度和不良左心室重构的独立因素。文章得出结论,BPV是一个可改变的危险因素,在特定区域需要进行干预。BPV是高血压治疗中一个重要的治疗靶点。风险优化和预防需要多学科方法,包括康复治疗,这将改善心血管状况和患者预后。