Kubicki S, Lenhard-Mazaheri P, Beyer K H
MMW Munch Med Wochenschr. 1977 Aug 26;119(34):1069-74.
Pentazocine dependencies are rare. In a period of 5 years, 60 were notified. The majority of these were not dependent. Of 46 utilizable notifications, 38 were false, 5 had taken pentazocine only temporarily or not at all. 19 received it for chronic or recurrent pains, 13 were polytoxicomaniacs, and 1 patient could not be classified. Only 8 cases could be referred to as pentazocine-dependent. The dose for addicts and polytoxicomaniacs was 11 ampoules daily on the average, almost three times as high as that for patients with painful diseases. Pentazocine dependencies are considerably less of a problem than those of opiates used up to now: withdrawal symptoms are slight, neglect and social dangers need scarely be considered. "Users" generally only turn to pentazocine when a painful disease supervenes. Dependency practically never occurs with oral administration.
喷他佐辛依赖较为罕见。在5年期间，共收到60例通报。其中大多数并非依赖者。在46份可利用的通报中，38份是误报，5例只是偶尔使用喷他佐辛或根本未使用。19例因慢性或复发性疼痛而使用，13例为多药滥用者，1例无法分类。只有8例可被称为喷他佐辛依赖者。成瘾者和多药滥用者的平均日剂量为11支安瓿，几乎是疼痛性疾病患者的三倍。与目前使用的阿片类药物相比，喷他佐辛依赖问题要小得多：戒断症状轻微，几乎无需考虑忽视和社会危害。“使用者”通常只有在患上疼痛性疾病时才会使用喷他佐辛。口服给药几乎不会产生依赖。
