Zink R M, Smith M F, Patton J L
J Hered. 1985 Nov-Dec;76(6):415-20. doi: 10.1093/oxfordjournals.jhered.a110136.
Recent studies have contrasted the expression of phenotypic traits, such as variance in morphological characters, with levels of genetic variation (heterozygosity) as determined by electrophoretic analysis of protein-coding loci. The theoretical basis for interpreting significant covariation stems in part from Lerner's work on genetic homeostasis, which predicts that within populations increased heterozygosity will produce decreased morphological variance, owing to a buffering effect of heterosis during development. However, the prediction for the relationship between genic heterozygosity and the variance of morphological traits among populations is unclear. To determine if a relationship existed between heterozygosity and morphological variance, we compared estimates of heterozygosity and morphological variance across 15 population samples of the fox sparrow and 17 samples of the pocket gopher. The estimates of morphological variance included coefficients of variation for each character and the variance of individual scores about the population mean in a principal components analysis. Although several recent studies have reported a significant relationship between heterozygosity and morphological variance, we found that the two measures do not covary significantly.
最近的研究将表型性状的表达，如形态特征的方差，与通过蛋白质编码位点的电泳分析确定的遗传变异水平（杂合度）进行了对比。解释显著协变的理论基础部分源于勒纳关于遗传稳态的研究，该研究预测，在种群内部，由于杂种优势在发育过程中的缓冲作用，杂合度增加会导致形态方差减小。然而，关于基因杂合度与种群间形态性状方差之间关系的预测尚不清楚。为了确定杂合度与形态方差之间是否存在关系，我们比较了狐雀的15个种群样本和囊鼠的17个样本的杂合度估计值和形态方差估计值。形态方差的估计值包括每个特征的变异系数以及主成分分析中个体得分相对于种群均值的方差。尽管最近的几项研究报告了杂合度与形态方差之间存在显著关系，但我们发现这两种测量方法并没有显著的协变关系。
