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孕期卵巢甲状腺肿的诊断与管理:一例报告

Diagnosis and Management of Struma Ovarii in Pregnancy: A Case Report.

作者信息

Narbona Arias Isidoro, Castaño Frías Lucia, Marfil Gonzalez María, Baños Cárdenas Laura, Jimenez Lopez Jesús S

机构信息

Obstetrics and Gynecology Department, Hospital Materno-Infantil, Hospital Regional Universitario Málaga, Avenida Arroyo de los Ángeles S/N, 29011 Málaga, Spain.

Research Group in Maternal-Foetal Medicine Epigenetics Women's Diseases and Reproductive Health, Biomedical Research Institute of Malaga (IBIMA), 29010 Málaga, Spain.

出版信息

Life (Basel). 2025 Aug 21;15(8):1328. doi: 10.3390/life15081328.

Abstract

Adnexal tumors during pregnancy are rare, with a prevalence ranging from 0.05% to 3%, and in most cases, they are benign. Struma ovarii, a monodermal teratoma, consists of over 50% thyroid tissue and accounts for 2.7% of ovarian teratomas. It typically affects women aged 40-60 and is exceptionally rare during pregnancy. Diagnosis is often only established after surgical intervention and histological examination. We present the case of a 39-year-old pregnant woman (gravida 2, para 1) at 19 weeks of gestation who presented with acute lower abdominal pain. At her first visit at 11 weeks, ultrasound revealed a 12 cm multilocular left adnexal mass. Initial conservative management was followed by emergency laparoscopy due to suspected ovarian torsion, resulting in a left oophorectomy. Histopathology confirmed struma ovarii. Thyroid function tests (TSH, FT4) remained within normal limits throughout pregnancy. The pregnancy continued without further complications, culminating in a spontaneous vaginal delivery at 40 + 4 weeks of a healthy female infant weighing 3800 g. Due to the rarity of this condition, treatment guidelines remain undefined, with management decisions relying on limited case reports and clinical judgment. This report highlights the importance of detailed evaluation and individualized management in such uncommon presentations during pregnancy.

摘要

孕期附件肿瘤较为罕见,患病率在0.05%至3%之间,且大多数情况下为良性。卵巢甲状腺肿是一种单胚层畸胎瘤,由超过50%的甲状腺组织构成,占卵巢畸胎瘤的2.7%。它通常影响40至60岁的女性,在孕期极为罕见。诊断往往仅在手术干预和组织学检查后才能确立。我们报告一例39岁的孕妇(孕2产1),妊娠19周时出现急性下腹痛。在11周首次就诊时,超声检查发现左附件有一个12厘米的多房性肿块。最初采取保守治疗,后因怀疑卵巢扭转进行了急诊腹腔镜检查,结果实施了左侧卵巢切除术。组织病理学证实为卵巢甲状腺肿。整个孕期甲状腺功能检查(促甲状腺激素、游离甲状腺素)均保持在正常范围内。妊娠继续进行且无进一步并发症,最终在40 + 4周时自然阴道分娩出一名体重3800克的健康女婴。由于这种情况罕见,治疗指南尚不明确,管理决策依赖于有限的病例报告和临床判断。本报告强调了在孕期此类罕见病例中进行详细评估和个体化管理的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40d9/12387300/a7c6d7c26aa6/life-15-01328-g001.jpg

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