Myers R R, James H E, Powell H C
J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1265-8. doi: 10.1136/jnnp.48.12.1265.
A model of endoneurial oedema is presented which produces localised nerve fibre injury including Wallerian degeneration, endoneurial oedema and increased endoneurial fluid pressure. A carbon dioxide laser was used to irradiate rat sciatic nerve and quantitative results were collected 2 days and 6 days after irradiation. The increase in endoneurial fluid pressure is compared with other models of Wallerian degeneration in which the entire fascicle was involved to aid in a comparative study of the role of oedema in neuropathy.
本文提出了一种神经内膜水肿模型，该模型可导致局部神经纤维损伤，包括华勒氏变性、神经内膜水肿和神经内膜液压升高。使用二氧化碳激光照射大鼠坐骨神经，并在照射后2天和6天收集定量结果。将神经内膜液压的升高与其他涉及整个束的华勒氏变性模型进行比较，以辅助对水肿在神经病变中作用的比较研究。
