Liu Yang-Fan, Chen Te-Li, Guo Jian-Wei, Liu Shih-Ching, Wang Wen-Ching
Department of Traumatology, Hsinchu MacKay Memorial Hospital, Hsinchu 300044, Taiwan.
Department of Thoracic Surgery, Hsinchu MacKay Memorial Hospital, Hsinchu 300044, Taiwan.
Medicina (Kaunas). 2025 Jul 26;61(8):1358. doi: 10.3390/medicina61081358.
Diabetes mellitus (DM) significantly impacts post-surgical recovery and fracture healing; however, few studies have specifically investigated the impact of DM on outcomes in patients undergoing surgical stabilization of rib fractures (SSRF). This study investigated the potential influence of DM on perioperative outcomes following SSRF, using data from Taiwan's National Health Insurance Research Database (NHIRD). Data of 1603 patients with multiple rib fractures who underwent SSRF between 2001 and 2019 were retrospectively analyzed. Patients were categorized into three groups: no DM, DM without chronic complications, and DM with chronic complications. The associations between DM status and perioperative outcomes, including hospital length of stay (LOS), in-hospital mortality, readmission rates, and complications such as pneumonia, surgical site infection (SSI), acute myocardial infarction (AMI), and total hospital costs were determined using univariate and multivariable regression analyses. The mean age of the 1603 patients was 52.0 years, and 71% were male. Patients with DM and chronic complications had higher risks of 14-day readmission (adjusted odds ratio [aOR] = 2.99; 95% confidence interval [CI]: 1.18-7.62), 15-30 day readmission (aOR = 3.28; 95% CI: 1.25-8.60), SSI (aOR = 2.90; 95% CI: 1.37-6.14), AMI (aOR = 3.44; 95% CI: 1.28-9.24), and acute respiratory distress syndrome (ARDS) (aOR = 1.96; 95% CI: 1.03-3.74). In conclusion, DM, particularly DM with chronic complications, significantly increases the risk of adverse short-term outcomes following SSRF. These findings emphasize the need for enhanced care for patients with DM to optimize the outcomes of SSRF.
糖尿病(DM)对术后恢复和骨折愈合有显著影响;然而,很少有研究专门调查DM对肋骨骨折手术固定(SSRF)患者预后的影响。本研究利用台湾国民健康保险研究数据库(NHIRD)的数据,调查了DM对SSRF围手术期预后的潜在影响。对2001年至2019年间接受SSRF的1603例多根肋骨骨折患者的数据进行了回顾性分析。患者被分为三组:无DM、无慢性并发症的DM和有慢性并发症的DM。使用单因素和多变量回归分析确定DM状态与围手术期预后之间的关联,包括住院时间(LOS)、院内死亡率、再入院率以及肺炎、手术部位感染(SSI)、急性心肌梗死(AMI)等并发症和总住院费用。1603例患者的平均年龄为52.0岁,71%为男性。有慢性并发症的DM患者14天再入院风险更高(调整优势比[aOR]=2.99;95%置信区间[CI]:1.18-7.62),15-30天再入院风险更高(aOR=3.28;95%CI:1.25-8.60),SSI风险更高(aOR=2.90;95%CI:1.37-6.14),AMI风险更高(aOR=3.44;95%CI:1.28-9.24),以及急性呼吸窘迫综合征(ARDS)风险更高(aOR=1.96;95%CI:1.03-3.74)。总之,DM,尤其是伴有慢性并发症的DM,显著增加了SSRF后不良短期预后的风险。这些发现强调了加强对DM患者的护理以优化SSRF预后的必要性。