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保加利亚高血压患者与健康相关的生活质量——基于人群的区域试点研究

Health-Related QoL of Hypertensive Patients in Bulgaria-Population-Based, Regional Pilot Study.

作者信息

Mitkova Zornitsa, Dimitrova Elena, Tomova Hristiana, Gerasimov Nikolay, Gospodinov Diyan, Mitov Konstantin, Pishev Stamen, Parashkevova Boryana, Petrova Guenka

机构信息

Department of Organization and Economy of Pharmacy, Faculty of Pharmacy, Medical University-Sofia, 1000 Sofia, Bulgaria.

National Cardiology Hospital Sofia, 1309 Sofia, Bulgaria.

出版信息

Medicina (Kaunas). 2025 Aug 17;61(8):1475. doi: 10.3390/medicina61081475.

Abstract

: The goal of this study is to assess health-related quality of life (HRQoL) using the EuroQoL (EQ-5D-5L) and identify factors that might contribute to it. : This is a real-life, observational study involving 234 hypertensive patients from Sofia and Burgas, conducted between January 2024 and July 2024. Patients were interviewed during their regular outpatient examinations and completed the questionnaire independently. : In total, 141 out of 234 respondents reported a visual analog scale (VAS) score of 70, and 152 reported a utility score of 0.7. The average VAS scores for males and females were 77.5 and 77.0, respectively, and the utility scores were 0.848 and 0.768, respectively. With advancing age, patients' quality of life (QoL) decreased from 0.879 to 0.652 utility. Respondents with higher levels of education had higher utility scores (0.848 for bachelor's/master's degrees vs. 0.542 for primary education). With an increase in the number of concomitant diseases and prescribed medications, the QoL decreased (0.848 vs. 0.623 and 0.848 vs. 0.736, respectively). : This first study of HRQoL using EQ-5D-5L among Bulgarian hypertensive patients revealed relatively high average VAS and utility scores. These results suggest that the disease is under control and that patients are being successfully treated and monitored. Factors such as comorbidity, residence, education, disability, and disease duration significantly affected and worsened patients' HRQoL.

摘要

本研究的目的是使用欧洲五维度健康量表(EQ-5D-5L)评估健康相关生活质量(HRQoL),并确定可能影响该质量的因素。这是一项在2024年1月至2024年7月期间对来自索非亚和布尔加斯的234名高血压患者进行的真实生活观察性研究。患者在定期门诊检查期间接受访谈,并独立完成问卷。在234名受访者中,共有141人报告视觉模拟量表(VAS)评分为70,152人报告效用评分为0.7。男性和女性的平均VAS评分分别为77.5和77.0,效用评分分别为0.848和0.768。随着年龄的增长,患者的生活质量(QoL)从0.879效用降至0.652效用。教育水平较高的受访者效用评分更高(本科/硕士学位为0.848,小学教育为0.542)。随着伴随疾病数量和处方药物数量的增加,生活质量下降(分别为0.848对0.623和0.848对0.736)。这项在保加利亚高血压患者中首次使用EQ-5D-5L进行的HRQoL研究显示,平均VAS和效用评分相对较高。这些结果表明该疾病得到了控制,患者得到了成功的治疗和监测。合并症、居住地、教育程度、残疾和病程等因素显著影响并恶化了患者的HRQoL。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71d1/12388286/bd181fac4228/medicina-61-01475-g001.jpg

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