He Jia, Yang Meng, Teng Zhongqiu, Wang Peng, Liang Junrong, Zou Yusheng, Wang Wen, Zhao Na, Qin Tian
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 102206, China.
Jiangxi Provincial Center for Disease Control and Prevention, Nanchang 330029, China.
Pathogens. 2025 Aug 4;14(8):770. doi: 10.3390/pathogens14080770.
, , and species are emerging tick-borne pathogens that cause zoonotic diseases, including rickettsiosis, anaplasmosis, and ehrlichiosis in both human and animal populations. This study aimed to investigate the prevalence of these pathogens in cattle-associated ticks from Ganzhou City, Jiangxi Province, China. Through molecular characterization using multilocus sequence analysis (16S , , , and genes), we analyzed 392 ticks collected from March to September in 2022. The PCR results showed that eight Rickettsiales bacteria were detected, including two species of (51/392, 13.0%), four species of (52/392, 13.3%), and two species of (70/392, 17.9%). Notably, the circulation of multiple pathogen species within populations demonstrates significant microbial diversity in this region. Further consideration and investigation should be given to the possible occurrence of rickettsiosis, ehrlichiosis, and anaplasmosis in humans and domestic animals. Our study provides critical baseline data for developing targeted surveillance strategies and informing public health interventions against tick-borne diseases in southeastern China.
立克次氏体属、无形体属和埃立希体属物种是新出现的蜱传病原体，可导致人畜共患病，包括人类和动物群体中的立克次体病、无形体病和埃立希体病。本研究旨在调查中国江西省赣州市牛相关蜱中这些病原体的流行情况。通过使用多位点序列分析（16S rRNA、gltA、groEL和ompA基因）进行分子特征分析，我们分析了2022年3月至9月收集的392只蜱。PCR结果显示，检测到8种立克次氏体目细菌，包括2种立克次氏体属（51/392，13.0%）、4种无形体属（52/392，13.3%）和2种埃立希体属（70/392，17.9%）。值得注意的是，立克次氏体群体中多种病原体物种的循环表明该地区存在显著的微生物多样性。应进一步考虑和调查人类和家畜中可能发生的立克次体病、埃立希体病和无形体病。我们的研究为制定针对性监测策略和为中国东南部蜱传疾病的公共卫生干预提供信息提供了关键的基线数据。
