Oros Nicușor Valentin, Repciuc Călin Cosmin, Bel Lucia Victoria, Melega Iulia, Pertea Andreea Niculina, Oana Liviu Ioan
Department of Internal Medicine, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Department of Surgery Anesthesiology and Intensive Care, Faculty of Veterinary Medicine, University of Agricultural Sciences and Veterinary Medicine, 400372 Cluj-Napoca, Romania.
Vet Sci. 2025 Aug 21;12(8):786. doi: 10.3390/vetsci12080786.
The therapeutic management of extensive skin wounds in cats can be time-consuming and require multiple therapeutic interventions, which can have significant financial implications for pet owners. Reconstructive surgery is often necessary to close skin defects with tissue loss to provide a quicker patient recovery. Conventional therapies like systemic antibiotics, anti-inflammatories, and local dressings are not always successful due to antibiotic resistance or a poor response, such as no or delayed healing. For more than a century, ozone has been utilized as an excellent disinfectant, but caution should be taken due to its oxidizing properties. Only in the past decade have numerous studies established therapeutic dose ranges for a wider medical use of ozone. The objective of this study was to clinically evaluate ozone therapy as a complementary treatment supporting and completing plastic and reconstructive surgery in 4 cats with extensive skin defects. The results obtained, following the local application of ozone therapy before and after skin reconstruction in our patients, encourage the use of ozone as a complementary therapy in the management of extensive skin wounds treated surgically by different reconstructive techniques.
猫大面积皮肤伤口的治疗管理可能耗时且需要多种治疗干预措施,这会给宠物主人带来重大经济负担。对于有组织缺损的皮肤缺损进行修复手术通常是必要的,以便患者更快康复。由于抗生素耐药性或反应不佳(如不愈合或愈合延迟),全身用抗生素、抗炎药和局部敷料等传统疗法并不总是成功的。一个多世纪以来,臭氧一直被用作一种优秀的消毒剂,但由于其氧化特性,应谨慎使用。仅在过去十年中,才有大量研究确定了臭氧更广泛医学用途的治疗剂量范围。本研究的目的是临床评估臭氧疗法作为一种辅助治疗方法,以支持和完善4只患有大面积皮肤缺损的猫的整形和重建手术。在我们的患者中,在皮肤重建前后局部应用臭氧疗法后获得的结果,鼓励将臭氧用作通过不同重建技术进行手术治疗的大面积皮肤伤口管理中的辅助疗法。