水痘-带状疱疹病毒感染及与水痘-带状疱疹病毒疫苗相关的眼部并发症
Varicella-Zoster Virus Infection and Varicella-Zoster Virus Vaccine-Related Ocular Complications.
作者信息
Yu Jing, Li Huihui, Ji Yuying, Liao Hailan
机构信息
Ophthalmology Department of the Second Affiliated Hospital, School of Medicine, The Chinese University of Hong Kong, Shenzhen & Longgang District People's Hospital of Shenzhen, Shenzhen 518172, China.
State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangzhou 510060, China.
出版信息
Vaccines (Basel). 2025 Jul 23;13(8):782. doi: 10.3390/vaccines13080782.
The varicella-zoster virus is a human herpesvirus that causes varicella as the primary infection and HZ as the reactivation of a latent infection. Ten to twenty percent of cases of herpes zoster ophthalmicus (HZO) involve the ophthalmic branch of the fifth cranial nerve. Any area of the eye may be affected by the condition. HZ has a lifetime risk of more than 30%. Complications from herpes zoster can significantly lower quality of life. The goal of HZ vaccinations is to stop HZ activation and PHN formation. Despite the uncommon possibility of side effects such as eye problems, the majority of vaccines on the market now are safe. The purpose of this review is to discuss VZV infection and analyze and summarize the ocular complications following VZV vaccination.
水痘带状疱疹病毒是一种人类疱疹病毒，它引起的原发性感染为水痘，而潜伏感染再激活则导致带状疱疹。10%至20%的眼部带状疱疹病例累及第五颅神经的眼支。眼部的任何区域都可能受该病症影响。带状疱疹的终身发病风险超过30%。带状疱疹的并发症会显著降低生活质量。带状疱疹疫苗接种的目标是阻止带状疱疹激活和带状疱疹后神经痛的形成。尽管存在眼部问题等罕见副作用的可能性，但目前市面上的大多数疫苗都是安全的。本综述的目的是讨论水痘带状疱疹病毒感染，并分析和总结水痘带状疱疹病毒疫苗接种后的眼部并发症。
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