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病例报告:乳头状肾细胞癌合并同侧肾结核。

Case Report: Papillary renal cell carcinoma complicated by ipsilateral renal tuberculosis.

作者信息

Tian Zhong, Zhu Cheng, Yang Tingting, Chen Shicheng, He Zhongcong, Han Guang, Chen Zhouhui, Zhang Neng, Yu Bo, Fu Ni

机构信息

Department of Urology, The Second Affiliated Hospital of Zunyi Medical University, Zunyi, China.

Department of Urology, The Affiliated Hospital of Zunyi Medical University, Zunyi, China.

出版信息

Front Med (Lausanne). 2025 Aug 12;12:1597849. doi: 10.3389/fmed.2025.1597849. eCollection 2025.

DOI:10.3389/fmed.2025.1597849
PMID:40873793
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12379642/
Abstract

Papillary renal cell carcinoma (PRCC) complicated by ipsilateral renal tuberculosis (TB) represents an exceptionally rare and complex clinical condition. Renal TB is the most common form of urogenital TB, while PRCC is the most prevalent histological subtype of non-clear cell renal cell carcinoma (RCC). In this study, we present the first reported case of PRCC complicated by ipsilateral renal TB, where the patient exhibited low back pain without hematuria. Initial imaging studies indicated a space-occupying lesion in the left kidney, raising suspicion of renal tumors. Subsequent postoperative pathology, immunohistochemical staining, and tuberculosis PCR results confirmed the diagnosis of PRCC complicated by ipsilateral renal TB.

摘要

乳头状肾细胞癌(PRCC)合并同侧肾结核(TB)是一种极为罕见且复杂的临床病症。肾结核是泌尿生殖系统结核最常见的形式,而PRCC是非透明细胞肾细胞癌(RCC)最常见的组织学亚型。在本研究中,我们报告了首例PRCC合并同侧肾结核的病例,该患者表现为腰痛但无血尿。最初的影像学检查显示左肾有占位性病变,怀疑为肾肿瘤。随后的术后病理、免疫组化染色及结核PCR结果证实诊断为PRCC合并同侧肾结核。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/c9a587777456/fmed-12-1597849-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/4afe21d6cc9f/fmed-12-1597849-g001.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/43b453ba0274/fmed-12-1597849-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/b3359ec4914e/fmed-12-1597849-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/c9a587777456/fmed-12-1597849-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/4afe21d6cc9f/fmed-12-1597849-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/1ece0a92fac0/fmed-12-1597849-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/21a8b2fd6ea4/fmed-12-1597849-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/a3e96a59de1d/fmed-12-1597849-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/43b453ba0274/fmed-12-1597849-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/b3359ec4914e/fmed-12-1597849-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0345/12379642/c9a587777456/fmed-12-1597849-g007.jpg

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本文引用的文献

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[Non-clear cell renal cell carcinoma].[非透明细胞肾细胞癌]
Urologie. 2024 Dec;63(12):1240-1245. doi: 10.1007/s00120-024-02473-6. Epub 2024 Nov 26.
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Renal Cell Carcinoma: A Review.肾细胞癌:综述。
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Renal cell carcinoma.肾细胞癌。
Lancet. 2024 Aug 3;404(10451):476-491. doi: 10.1016/S0140-6736(24)00917-6. Epub 2024 Jul 18.
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Case report: Sarcomatoid renal cell carcinoma masquerading as hydronephrosis.病例报告:伪装成肾积水的肉瘤样肾细胞癌。
Front Oncol. 2024 May 22;14:1361250. doi: 10.3389/fonc.2024.1361250. eCollection 2024.
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Progress in mechanism-based diagnosis and treatment of tuberculosis comorbid with tumor.结核病合并肿瘤的基于机制的诊断与治疗进展。
Front Immunol. 2024 Jan 17;15:1344821. doi: 10.3389/fimmu.2024.1344821. eCollection 2024.
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The Role of CT Imaging in Characterization of Small Renal Masses.CT成像在小肾肿块特征描述中的作用。
Diagnostics (Basel). 2023 Jan 17;13(3):334. doi: 10.3390/diagnostics13030334.
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Epidemiology of Renal Cell Carcinoma: 2022 Update.肾细胞癌的流行病学:2022 年更新。
Eur Urol. 2022 Nov;82(5):529-542. doi: 10.1016/j.eururo.2022.08.019. Epub 2022 Sep 10.
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The 2022 World Health Organization Classification of Tumours of the Urinary System and Male Genital Organs-Part A: Renal, Penile, and Testicular Tumours.2022 年世界卫生组织泌尿系统和男性生殖器官肿瘤分类 - 第 A 部分:肾脏、阴茎和睾丸肿瘤。
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