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[高剂量率腔内照射子宫颈癌引起的胃肠道并发症]

[Gastrointestinal complications caused by high-dose-rate intracavitary irradiation of carcinoma of the uterine cervix].

作者信息

Nishikawa K, Koga K, Mizoguchi N, Kono M, Kuroki T, Yasuda H, Mori N, Watanabe K

出版信息

Gan No Rinsho. 1985 Nov;31(14):1810-3.

PMID:4087388
Abstract

We treated 64 patients with carcinoma of the uterine cervix with high-dose-rate intracavitary irradiation between 1978 and 1984. Of the 52 patients who were followed for more than two years, gastrointestinal complications occurred in 11 (21%): six grade I patients (12%), two grade II patients (4%) and three grade III patients (6%). The patients were graded according to the severity of the complications. The three patients with grade III complications underwent emergency surgery because of ileus or perforation of the gastrointestinal tract. It is suggested that these severe complications are liable to occur in patients given more than seven fractions of intracavitary irradiation in a fraction dose of 6 Gy to point A or previously operated on in the pelvic cavity. Accurate center shield in relation to tandem sources is also emphasized.

摘要

1978年至1984年间,我们对64例子宫颈癌患者进行了高剂量率腔内照射治疗。在52例随访超过两年的患者中,11例(21%)出现了胃肠道并发症:6例I级患者(12%)、2例II级患者(4%)和3例III级患者(6%)。根据并发症的严重程度对患者进行分级。3例III级并发症患者因肠梗阻或胃肠道穿孔接受了急诊手术。提示腔内照射A点分次剂量6Gy以上超过7次或盆腔先前接受过手术的患者易发生这些严重并发症。同时强调了与串联源相关的精确中心屏蔽。

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