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一种用于心血管风险预测的统一混合模型:融合统计、基于核和神经方法。

A Unified Hybrid Model for Cardiovascular Risk Prediction: Merging Statistical, Kernel-Based and Neural Approaches.

作者信息

Khan Mudassir, Mahajan Rupali A, Sivakumar Nithya Rekha, Gulhane Monali, Rakesh Nitin, Dey Rajesh, Uddin Md Salah, Basheer Shakila

机构信息

Department of Computer Science, College of Computer Science, Applied College Tanumah, King Khalid University, Abha, Saudi Arabia.

Vishwakarma Institute of Technology, Pune, India.

出版信息

J Cell Mol Med. 2025 Aug;29(16):e70797. doi: 10.1111/jcmm.70797.

DOI:10.1111/jcmm.70797
PMID:40874542
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12392130/
Abstract

Cardiovascular diseases (CVDs) are still the leading cause of death in the worldwide. Traditional machine learning models often have difficulty in determine how to capture the complex links between disease risk factors and disease occurrence. This article discusses a hybrid machine learning approach for cardiovascular risk prediction (HMLCRP) to address this problem. This approach combines logistic regression (LR), support vector machines (SVMs) and neural networks (NNs) to make predictions more correct and reliable. The proposed model looks at important coronary heart sickness risk factors, including excessive blood pressure, a record of coronary heart disorder within the family, pressure, age, sex, levels of cholesterol, body mass index (BMI) and poor dwelling choices. The hybrid technique makes use of the nice functions of LR for clean understanding, SVM for dealing with large amounts of facts and NNs for finding developments. By integrating these models together, the HMLCRP makes positive that type is correct and that danger predictions are accurate. In this study, benchmark datasets used, which include the cardio statistics set, heart ailment dataset and Framingham heart examination dataset, are used to train and test the version. Popular parameter measures, such as accuracy, precision, recall and the F1-score, are used to determine overall performance. The results of the experiments indicate that the HMLCRP is better at predicting effects than individual models. The suggested combination model is a major step forward in personalised healthcare because it allows proactive risk management and early intervention methods to stop CVD.

摘要

心血管疾病(CVDs)仍是全球范围内的主要死因。传统的机器学习模型在确定如何捕捉疾病风险因素与疾病发生之间的复杂联系时常常存在困难。本文讨论了一种用于心血管风险预测的混合机器学习方法(HMLCRP)来解决这一问题。这种方法结合了逻辑回归(LR)、支持向量机(SVMs)和神经网络(NNs),以使预测更加准确和可靠。所提出的模型考虑了重要的冠心病风险因素,包括高血压、家族冠心病史、压力、年龄、性别、胆固醇水平、体重指数(BMI)以及不良的生活选择。这种混合技术利用了LR易于理解的优点、SVM处理大量数据的能力以及NNs发现趋势的能力。通过将这些模型整合在一起,HMLCRP确保分类正确且风险预测准确。在本研究中,所使用的基准数据集,包括心脏数据集、心脏病数据集和弗雷明汉心脏研究数据集,被用于训练和测试该模型。常用的参数指标,如准确率、精确率、召回率和F1分数,被用来确定整体性能。实验结果表明,HMLCRP在预测效果方面比单个模型更好。所建议的组合模型是个性化医疗领域向前迈出的重要一步,因为它允许进行主动风险管理和早期干预措施以预防心血管疾病。

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本文引用的文献

1
Optimized machine learning framework for cardiovascular disease diagnosis: a novel ethical perspective.用于心血管疾病诊断的优化机器学习框架:一种新的伦理视角。
BMC Cardiovasc Disord. 2025 Feb 20;25(1):123. doi: 10.1186/s12872-025-04550-w.
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Optimized Clinical Feature Analysis for Improved Cardiovascular Disease Risk Screening.优化临床特征分析以改善心血管疾病风险筛查
IEEE Open J Eng Med Biol. 2024 Jan 29;5:816-827. doi: 10.1109/OJEMB.2023.3347479. eCollection 2024.
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Artificial intelligence in the risk prediction models of cardiovascular disease and development of an independent validation screening tool: a systematic review.
人工智能在心血管疾病风险预测模型中的应用及独立验证筛选工具的开发:系统评价。
BMC Med. 2024 Feb 5;22(1):56. doi: 10.1186/s12916-024-03273-7.
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Machine learning to predict cardiovascular risk.机器学习预测心血管风险。
Int J Clin Pract. 2019 Oct;73(10):e13389. doi: 10.1111/ijcp.13389. Epub 2019 Aug 4.