Jalil Riad Abdel, Alshwayyat Sakhr, Haddad Hussam, Al-Kurdi Mohammed Al-Mahdi
Department of General Surgery, King Hussein Cancer Center, Amman, Jordan; Department of Surgery, King Hussein Cancer Centre, Amman, Jordan.
Kern Medical (UCLA David Geffen School of Medicine affiliate), Bakersfield, California, USA; King Hussein Cancer Center, Amman, Jordan; Princess Basma Teaching Hospital, Irbid, Jordan; Applied Science Research Center, Applied Science Private University, Amman, Jordan.
Int J Surg Case Rep. 2025 Aug 26;135:111832. doi: 10.1016/j.ijscr.2025.111832.
Endobronchial solitary fibrous tumors (SFTs) are rare mesenchymal neoplasms that account for less than 2 % of all SFTs. Diagnosis and treatment are major challenges because of their rarity and varied presentation. We present a case of endobronchial SFT that was successfully treated with minimally invasive bronchoscopic excision and review the literature to highlight the latest developments in diagnosis and treatment.
A 45-year-old female was referred for an incidental finding of bronchial lesion on imaging. Chest computed tomography (CT) revealed a well-defined, noncalcified, obstructive lesion in the left upper lobe bronchus. Flexible bronchoscopy confirmed complete airway obstruction, and the tumor was excised using a hot snare. Histopathological examination revealed a low-risk solitary fibrous tumor with immunohistochemical positivity for CD34 and Bcl-2, confirming SFT. Follow-up imaging and clinical follow-up for three years showed no recurrence.
We highlight the relevance of advanced imaging, histopathological examination, and multimodal management for the diagnosis and treatment of endobronchial SFTs. Minimally invasive bronchoscopic excision is a safe and effective treatment modality for localized lesions.
This literature review underlines the need for long-term surveillance because of the tendency for malignant transformation. Documenting these infrequent cases improves diagnostic and therapeutic strategies for endobronchial SFTs.
支气管内孤立性纤维瘤(SFTs)是罕见的间叶性肿瘤,占所有SFTs的比例不到2%。由于其罕见性和表现多样,诊断和治疗是重大挑战。我们报告一例经微创支气管镜切除成功治疗的支气管内SFT病例,并回顾文献以突出诊断和治疗的最新进展。
一名45岁女性因影像学检查偶然发现支气管病变而就诊。胸部计算机断层扫描(CT)显示左上叶支气管有一个边界清晰、无钙化的阻塞性病变。柔性支气管镜检查证实气道完全阻塞,使用热圈套器切除肿瘤。组织病理学检查显示为低风险孤立性纤维瘤,CD34和Bcl-2免疫组化呈阳性,确诊为SFT。三年的随访影像学检查和临床随访显示无复发。
我们强调先进影像学检查、组织病理学检查和多模式管理在支气管内SFT诊断和治疗中的相关性。微创支气管镜切除是治疗局限性病变的一种安全有效的治疗方式。
这篇文献综述强调了由于存在恶性转化倾向而进行长期监测的必要性。记录这些罕见病例可改善支气管内SFT的诊断和治疗策略。