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自然流产和人工流产后Rh免疫球蛋白的应用

Rh immunoglobulin utlization after spontaneous and induced abortion.

作者信息

Grimes D A, Ross W C, Hatcher R A

出版信息

Obstet Gynecol. 1977 Sep;50(3):261-3.

PMID:408768
Abstract

To monitor the utilization of Rh immunoglobulin (RhIG), we reviewed the charts of 389 spontaneous and 1350 induced abortion patients treated in 1975 at a metropolitan hospital. The rate of ascertainment of Rh type was significantly higher for induced (99.6%) than for spontaneous abortion patients (95.1%) (P less than 0.001). Utilization of Rh immunoglobulin (RhIG) also was significantly higher for induced (98.9%) than for spontaneous abortion patients (80.6%) (P less than 0.001). Women at risk who did not receive RhIG after spontaneous abortion were mostly young, of low gravidity, and at gestational ages (mean 14.4 weeks) associated with substantial risks of Rh sensitization. Eradication of Rh hemolytic disease requires improvement in the system of identifying and treating patients who need prophylaxis.

摘要

为监测Rh免疫球蛋白(RhIG)的使用情况,我们查阅了1975年在一家大都市医院接受治疗的389例自然流产患者和1350例人工流产患者的病历。人工流产患者的Rh血型确定率(99.6%)显著高于自然流产患者(95.1%)(P<0.001)。Rh免疫球蛋白(RhIG)的使用率人工流产患者(98.9%)也显著高于自然流产患者(80.6%)(P<0.001)。自然流产后未接受RhIG的高危女性大多年轻、妊娠次数少,且处于与Rh致敏风险较高相关的孕周(平均14.4周)。根除Rh溶血病需要改进识别和治疗需要预防的患者的系统。

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