胃同时发生的胃癌和神经内分泌肿瘤：3例罕见病例系列报道及文献复习
Concomitant gastric cancer and neuroendocrine tumours in the stomach: a rare case series of 3 patients and a literature review.
作者信息
Liu Luyu, Ding Weilu, Wang Zhenzhen, Wang Gongning, Er Limian
机构信息
Department of Endoscopy, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
Department of Thoracic Surgery, The Fourth Hospital of Hebei Medical University, Shijiazhuang, 050000, Hebei, China.
出版信息
Diagn Pathol. 2025 Aug 29;20(1):100. doi: 10.1186/s13000-025-01704-4.
BACKGROUND
Concomitant gastric cancer and neuroendocrine tumours in the stomach are very rare, and their clinical characteristics, pathogenesis and treatment principles remain poorly understood.
CASE PRESENTATION
We present three cases of concomitant gastric cancer and neuroendocrine tumours in the stomach, all of which were pathologically diagnosed through endoscopy and biopsy. One patient received total gastrectomy, while the other two patients underwent endoscopic resection. Moreover, the diagnostic characteristics and treatment of synchronous gastric cancer and neuroendocrine tumours are summarized and analysed in combination with a study of 8 cases.
CONCLUSIONS
G1 NET may be more likely to be concomitant with gastric cancer. Endoscopic resection is the preferred treatment for patients with synchronous early gastric cancer and NETs.
背景
胃同时发生的胃癌和神经内分泌肿瘤非常罕见，其临床特征、发病机制及治疗原则仍知之甚少。
病例报告
我们呈现三例胃同时发生的胃癌和神经内分泌肿瘤病例，所有病例均通过内镜检查及活检进行病理诊断。一名患者接受了全胃切除术，另外两名患者接受了内镜下切除。此外，结合8例病例的研究，对同步性胃癌和神经内分泌肿瘤的诊断特点及治疗进行了总结和分析。
结论
G1级神经内分泌肿瘤可能更易与胃癌同时发生。内镜下切除是同步性早期胃癌和神经内分泌肿瘤患者的首选治疗方法。
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