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[利用绒毛膜绒毛进行遗传性疾病的产前诊断]

[Prenatal diagnosis of hereditary diseases using chorionic villi].

作者信息

Rumenić-Garzicić L, Krajinović M

出版信息

Jugosl Ginekol Perinatol. 1985 Jan-Apr;25(1-2):25-8.

PMID:4087929
Abstract

The paper is based on the first results of a preliminary study of the cytogenetic analysis of chorionic villi samples. Chorionic villi were obtained from 31 women undergoing artificial abortion in the first trimester of pregnancy. The tissue was used for direct chromosome preparations and sex-chromatin examinations (X and Y body). The results suggest the possibility of a simple and quick prenatal determination of fetal sex in the first trimester and the provision of a sufficient number of mitosis with well-spread chromosomes. This new method may become the method of choice in prenatal diagnosis after being thoroughly examined and verified.

摘要

本文基于对绒毛膜绒毛样本进行细胞遗传学分析的初步研究的首批结果。绒毛膜绒毛取自31名妊娠早期接受人工流产的妇女。该组织用于直接染色体制备和性染色质检查(X和Y小体)。结果表明,在妊娠早期简单快速地产前确定胎儿性别并提供足够数量的有丝分裂且染色体分散良好是有可能的。这种新方法经过全面检查和验证后可能成为产前诊断的首选方法。

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