Slon-Roblero Maria Fernanda, Stel Vianda S, Sanchez-Alvarez Emilio, Escola Joaquín Manrique, Dias Bruno José Fraga, Auñón Antonio Sarrión, Ferraro Pietro Manuel, De Meester Johan M, Boyer Annabel, Rydell Helena, Hommel Kristine, Åsberg Anders, Arias Inés Rama, Methven Shona, Huete María José Espigares, Abrahams Alferso C, Palsson Runolfur, Goffin Eric, Aresté-Fosalba Nuria, Bello Aisha J, Kuzema Viktorija, Helve Jaakko, Kerschbaum Julia, Bakkaloglu Sevcan A, Kislikova Maria, Jager Kitty J, Ortiz Alberto, Kramer Anneke
Department of Nephrology, Hospital Universitario de Navarra, Pamplona, Spain.
ERA Registry, Department of Medical Informatics, Amsterdam UMC - location University of Amsterdam, Amsterdam, The Netherlands.
Nephrol Dial Transplant. 2025 Aug 29. doi: 10.1093/ndt/gfaf171.
Home dialysis therapies could offer benefits to individuals undergoing dialysis. This study examines trends of home dialysis, including home haemodialysis (HHD) and peritoneal dialysis (PD) across European countries from 2012 to 2021, and evaluates transitions between home dialysis and other kidney replacement therapies (KRT).
Data from adult patients undergoing KRT in 13 European countries were obtained from the European Renal Association (ERA) Registry. Trends in home dialysis initiation, the number of patients receiving home dialysis by December 31st of each year, and transitions before and after home dialysis were analysed.
Between 2012 and 2021, 65 246 adults initiated PD and 7 878 HHD. Over the last decade, HHD initiation rates and prevalence increased, while those for PD declined, resulting in a stable overall home dialysis initiation rate and prevalence. Home dialysis accounted for 5.8% of the total KRT prevalence. Most HHD patients transitioned from in-centre HD (ICHD, 76.6%), whereas 86.9% of PD patients had no prior KRT. Two years after initiation, 53.2% of HHD patients remained on HHD, 20.9% received a kidney transplant (KT), 16.6% transitioned to ICHD, 8.1% died while on HHD, and 0.6% switched to PD. Among PD patients, 39.6% remained on PD, 22.6% transitioned to ICHD, 18.3% received a KT, 17.4% died while on PD and 0.3% switched to HHD.
While the use of HHD over the past decade increased in some European countries, the use of PD has declined. The prevalence of both HHD and PD remains low, with limited transitions from other KRT options to home dialysis and between home dialysis modalities. These findings highlight the need for more effective, region-specific strategies to improve access to these modalities for patients who may benefit from it.
家庭透析疗法可为接受透析的个体带来益处。本研究考察了2012年至2021年欧洲各国家庭透析的趋势,包括家庭血液透析(HHD)和腹膜透析(PD),并评估了家庭透析与其他肾脏替代疗法(KRT)之间的转换情况。
从欧洲肾脏协会(ERA)登记处获取了13个欧洲国家接受KRT的成年患者的数据。分析了家庭透析开始的趋势、每年12月31日接受家庭透析的患者数量以及家庭透析前后的转换情况。
2012年至2021年期间,65246名成年人开始进行腹膜透析,7878人开始进行家庭血液透析。在过去十年中,家庭血液透析的起始率和患病率有所上升,而腹膜透析的起始率和患病率则有所下降,导致家庭透析的总体起始率和患病率保持稳定。家庭透析占肾脏替代疗法总患病率的5.8%。大多数家庭血液透析患者由中心血液透析(ICHD)转换而来(76.6%),而86.9%的腹膜透析患者此前未接受过肾脏替代疗法。开始透析两年后,53.2%的家庭血液透析患者仍接受家庭血液透析,20.9%接受了肾移植(KT),16.6%转换为中心血液透析,8.1%在接受家庭血液透析期间死亡,0.6%转换为腹膜透析。在腹膜透析患者中,39.6%仍接受腹膜透析,22.6%转换为中心血液透析,18.3%接受了肾移植,17.4%在接受腹膜透析期间死亡,0.3%转换为家庭血液透析。
虽然在过去十年中,一些欧洲国家家庭血液透析的使用有所增加,但腹膜透析的使用却有所下降。家庭血液透析和腹膜透析的患病率仍然较低,从其他肾脏替代疗法转换为家庭透析以及在家庭透析模式之间转换的情况有限。这些发现凸显了需要制定更有效的、针对特定地区的策略,以改善可能从中受益的患者获得这些透析模式的机会。