Fu Tingkui, Wu Xiuqin, Yu Biao
Department of Intensive Care Unit, The Second Hospital of Nanjing, Affiliated to Nanjing University of Chinese Medicine, Nanjing, China.
Department of Operating Room, The Affiliated Jiangning Hospital of Nanjing Medical University, Nanjing, China.
Front Med (Lausanne). 2025 Aug 13;12:1644290. doi: 10.3389/fmed.2025.1644290. eCollection 2025.
Pressure injury prevention is clinically critical for optimizing patient outcomes. This meta-analysis systematically evaluates the efficacy of silicone foam dressings in preventing pressure injuries specifically in the sacral and heel regions.
A comprehensive literature search was conducted across PubMed, Embase, ClinicalTrials.gov, the Cochrane Library, Web of Science, China National Knowledge Infrastructure (CNKI), Wanfang, and Weipu Databases, spanning from database inception to May 10, 2025. Eligible studies were randomized controlled trials (RCTs) investigating silicone foam dressings for pressure injury prevention. Meta-analyses were performed using RevMan 5.4 software.
Ten RCTs involving 4,817 patients were included, with 2,670 patients in the silicone foam dressing intervention group. Meta-analysis results showed that silicone foam dressings significantly reduced the incidence of stage I pressure injuries in the sacral region [relative risk (RR) = 0.18, 95% confidence interval (CI): 0.09-0.33, < 0.001] and heel region (RR = 0.30, 95% CI: 0.14-0.66, = 0.003). Additionally, these dressings decreased the incidence of stage II and more severe pressure injuries in the sacral region (RR = 0.42, 95% CI: 0.31-0.58, < 0.001) and heel region (RR = 0.52, 95% CI: 0.27-0.99, = 0.05).
Silicone foam dressings exhibit significant efficacy in reducing pressure injury incidence in the sacral and heel regions, supporting their clinical recommendation. However, further research is required to explore their cost-effectiveness and long-term outcomes to strengthen evidence for broader implementation.
压力性损伤的预防对于优化患者预后在临床上至关重要。本荟萃分析系统评价了硅胶泡沫敷料在预防特别是骶部和足跟部压力性损伤方面的疗效。
对PubMed、Embase、ClinicalTrials.gov、Cochrane图书馆、Web of Science、中国知网（CNKI）、万方和维普数据库进行全面的文献检索，检索时间跨度从各数据库建库至2025年5月10日。纳入的合格研究为调查硅胶泡沫敷料预防压力性损伤的随机对照试验（RCT）。使用RevMan 5.4软件进行荟萃分析。
纳入了10项涉及4817例患者的RCT，硅胶泡沫敷料干预组有2670例患者。荟萃分析结果显示，硅胶泡沫敷料显著降低了骶部I期压力性损伤的发生率[相对危险度（RR）=0.18，95%置信区间（CI）：0.09 - 0.33，P<0.001]和足跟部I期压力性损伤的发生率（RR = 0.30，95%CI：0.14 - 0.66，P = 0.003）。此外，这些敷料降低了骶部II期及更严重压力性损伤的发生率（RR = 0.42，95%CI：0.31 - 0.58，P<0.001）和足跟部II期及更严重压力性损伤的发生率（RR = 0.52，95%CI：0.27 - 0.99，P = 0.05）。
硅胶泡沫敷料在降低骶部和足跟部压力性损伤发生率方面显示出显著疗效，支持其临床推荐。然而，需要进一步研究以探讨其成本效益和长期结局，以加强更广泛应用的证据。
