Zhang James, Nagamine Todd, Vu Kimberly, Ali Mohammed, Limpruttidham Nath, Gozun Maan, Moreno Jesus Pino, Banerjee Dipanjan
Department of Cardiovascular Medicine, University of Washington, Seattle, WA 98195, United States.
Department of Medicine, The John A Burns School of Medicine, University of Hawai'i, Honolulu, HI 96813, United States.
World J Transplant. 2025 Sep 18;15(3):102078. doi: 10.5500/wjt.v15.i3.102078.
Advanced heart failure and transplant (AHFTC) teams are crucial in the management of patients in cardiogenic shock. We sought to explore the impact of AHFTC physicians on outcomes in patients receiving extracorporeal membrane oxygenation (ECMO) support.
To determine whether outcomes differ in the care of ECMO patients when AHFTC physicians serve in a primary consultative role.
We conducted a retrospective cohort study of 51 patients placed on veno-venous (VV) and veno-arterial (VA) ECMO between January 2015 and February 2023 at our institution. We compared ECMO outcomes between teams managed primarily by intensivists teams where AHFTC physicians played a direct role in ECMO management, including patient selection. Our primary outcome measure was survival to 30 days post hospital discharge.
For combined VA and VV ECMO patients, survival to 30 days post discharge in the AHFTC cohort was significantly higher (67% 30%, = 0.01), largely driven by a significantly increased 30-day post discharge survival in VA ECMO patients in the AHFTC group (64% 20%, = 0.05).
This study suggests that patients in shock requiring VA ECMO support may have improved survival 30 days after hospital discharge when an AHFTC team serves in a direct role in the selection and management of patients. Further studies are needed to validate this impact.
晚期心力衰竭与移植(AHFTC)团队在心源休克患者的管理中至关重要。我们试图探讨AHFTC医生对接受体外膜肺氧合(ECMO)支持患者预后的影响。
确定当AHFTC医生担任主要咨询角色时,ECMO患者的护理结果是否存在差异。
我们对2015年1月至2023年2月在我院接受静脉-静脉(VV)和静脉-动脉(VA)ECMO治疗的51例患者进行了回顾性队列研究。我们比较了主要由重症监护医生管理的团队与AHFTC医生在ECMO管理(包括患者选择)中发挥直接作用的团队之间的ECMO治疗结果。我们的主要结局指标是出院后30天的生存率。
对于VA和VV ECMO联合治疗的患者,AHFTC队列出院后30天的生存率显著更高(67%对30%,P = 0.01),这主要是由于AHFTC组VA ECMO患者出院后30天生存率显著提高(64%对20%,P = 0.05)。
本研究表明,当AHFTC团队在患者选择和管理中发挥直接作用时,需要VA ECMO支持的休克患者出院后30天的生存率可能会提高。需要进一步研究来验证这种影响。