Sims Daniel B, Kim Yekaterina, Kalininskiy Aleksandr, Yanamandala Mounica, Josephs Joshua, Rivas-Lasarte Mercedes, Ahmed Navid, Assa Andrei, Jahufar Fathima, Kumar Salil, Sun Eric, Rahgozar Kusha, Ali Syed Zain, Zhang Ming, Patel Shreyans, Edwards Pauline, Saeed Omar, Shin J Julia, Murthy Sandhya, Patel Snehal, Shah Aman, Jorde Ulrich P
Division of Cardiology.
Department of Medicine, Montefiore Medical Center, Bronx, New York.
J Card Fail. 2022 Mar;28(3):394-402. doi: 10.1016/j.cardfail.2021.09.013. Epub 2021 Oct 9.
Cardiac intensive care units (CICUs) serve medically complex patients with multiorgan dysfunction. Whether a CICU that is staffed full time by heart failure (HF) specialists is associated with decreased mortality is unclear.
A retrospective review of consecutive CICU admissions from January 1, 2012, to December 31, 2016, was performed. In January 2014, the CICU changed from an open unit staffed by any cardiologist to a closed unit managed by HF specialists. Patients' baseline characteristics were determined, and a multivariate regression analysis was performed to ascertain mortality rates in the CICU. Baseline severity of illness was higher in the closed/HF specialist CICU model (P< 0.001). Death occurred in 101 of 1185 patients admitted to the CICU (8.5%) in the open-unit model and in 139 of 2163 patients (6.4%) admitted to the closed/HF specialist model (absolute risk reduction 2.1%, 95% confidence interval [CI] 0.1-4.0%; P = 0.01). The transition from an open to a closed/HF specialist model was associated with a lower overall CICU mortality rate (odds ratio [OR] 0.63; 95% CI 0.43-0.93). Prespecified interaction with a mechanical circulatory support device and unit model showed that treatment with such a device was associated with lower mortality rates in the closed/HF specialist model of a CICU (OR 0.6; 95% CI 0.18-0.78; P for interaction <0.01).
Transition to a closed unit model staffed by a dedicated HF specialist is associated with lower CICU mortality rates.
心脏重症监护病房(CICU)收治患有多器官功能障碍的病情复杂的患者。由心力衰竭(HF)专科医生全职配备人员的CICU是否与死亡率降低相关尚不清楚。
对2012年1月1日至2016年12月31日连续入住CICU的患者进行回顾性研究。2014年1月,CICU从由任何心脏病专家配备人员的开放式病房转变为由HF专科医生管理的封闭式病房。确定患者的基线特征,并进行多因素回归分析以确定CICU的死亡率。在封闭式/HF专科医生CICU模式下,疾病的基线严重程度更高(P<0.001)。在开放式病房模式下,1185例入住CICU的患者中有101例死亡(8.5%),在封闭式/HF专科医生模式下,2163例患者中有139例死亡(6.4%)(绝对风险降低2.1%,95%置信区间[CI]0.1-4.0%;P = 0.01)。从开放式病房模式转变为封闭式/HF专科医生模式与CICU总体死亡率降低相关(优势比[OR]0.63;95%CI 0.43-0.93)。预先设定的与机械循环支持装置和病房模式的相互作用表明,在CICU的封闭式/HF专科医生模式下,使用这种装置进行治疗与较低的死亡率相关(OR 0.6;95%CI 0.18-0.78;相互作用P<0.01)。
转变为由专职HF专科医生配备人员的封闭式病房模式与CICU死亡率降低相关。