Muchmore Samuel, Olorunda Olufemi, Ashine Abinet
Department of Internal Medicine, Good Samaritan Regional Medical Center, Corvallis, Oregon, USA.
Division of Cardiology, Samaritan Health Services, Corvallis, Oregon, USA.
JACC Case Rep. 2025 Aug 27;30(25):104821. doi: 10.1016/j.jaccas.2025.104821.
Pericardial decompression syndrome is a rare but potentially life-threatening complication of pericardiocentesis. It is characterized by myocardial dysfunction that leads to hemodynamic instability and acute heart failure.
A 24-year-old woman was admitted for a large malignant pericardial effusion. After drainage of this effusion, she had hemodynamic instability, with severe right ventricular dysfunction and impaired left ventricular filling. Spontaneous improvement was seen after 10 days of supportive care.
The exact pathophysiology behind this condition is not well understood, however this case highlights the impact that right ventricular dilation can have on left ventricular filling and cardiac output.
TAKE-HOME MESSAGES: Pericardial decompression syndrome is a rare but life-threatening complication of pericardial drainage. A slower drainage approach is recommended for large effusions.
心包减压综合征是心包穿刺术一种罕见但可能危及生命的并发症。其特征为心肌功能障碍，导致血流动力学不稳定和急性心力衰竭。
一名24岁女性因大量恶性心包积液入院。该积液引流后，她出现血流动力学不稳定，伴有严重右心室功能障碍和左心室充盈受损。经过10天的支持治疗后病情自发改善。
这种情况背后的确切病理生理学机制尚不完全清楚，不过该病例突出了右心室扩张对左心室充盈和心输出量的影响。
心包减压综合征是心包引流一种罕见但危及生命的并发症。对于大量积液，建议采用更缓慢的引流方法。
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